Centre for Heart Failure, Transplantation and Extracorporeal Support

2025

Staged mechanical circulatory support in paediatric HIT: Bivalirudin anticoagulation across ECMO, VAD, and cardiac transplantation.

Beeman A., Issitt R., Mathias M., Cohen M., Laurence C., Muthialu N., Kostolny M., Thiruchelvam T.

Perfusion, 2025

ABO-incompatible heart transplants in children aged 2-9 years: A new paradigm in transplant?

Hollis P., Issitt R., Lava S., Laurence C., Simmonds J., Fenton M., Muthialu N., Robertson A., Crook R., West L., Burch M.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2025

Towards goal-directed perfusion - Part II: Temperature dependence of Q

Sharabiani M., Mahani A., Issitt R., Srinivasan Y., Bottle A., Stoica S.

Perfusion, 2025

Towards goal-directed perfusion - Part I: Developing physiology-inspired mathematical framework using high-resolution paediatric CPB data.

Sharabiani M., Mahani A., Issitt R., Srinivasan Y., Bottle A., Stoica S.

Perfusion, 2025

An investigation into the contributing factors to survival of ARDS patients supported by veno-venous ECMO.

Majithia-Beet G., Naemi R., Issitt R.

Perfusion, 2025

Association between NT-proBNP changes and clinical outcomes in paediatric patients with heart failure: Insights from PANORAMA-HF and PARADIGM-HF.

Shaddy R., Gong J., Garito T., Solar-Yohay S., Zhang S., Prescott M., Bonnet D., Kantor P., Burch M., Mao C., Cilliers A., Canter C., Law Y., Grutter G., Wang J., Jeewa A., Rossano J.

ESC heart failure, 2025

Slide Tracheoplasty in Long Segment Tracheobronchial Stenosis.

Beeman A., Ramaswamy M., Thiruchelvam T., Forshaw N., Ip J., Hewitt R., Muthialu N.

The Annals of thoracic surgery, 2025

GenAI exceeds clinical experts in predicting acute kidney injury following paediatric cardiopulmonary bypass.

Sharabiani M., Mahani A., Bottle A., Srinivasan Y., Issitt R., Stoica S.

Scientific reports, 2025

Clinical grade expansion protocol for the manufacture of thymus-derived Treg cells for clinical application.

Fanelli G., Marks P., Aiyengar A., Romano M., Gooljar S., Kumar S., Burch M., Lombardi G.

Journal of translational medicine, 2025

Dual immunoadsorption for ABO-incompatible heart transplantation in a 35 kg child.

Crook R., Cohen M., Mimic B., Fenton M., Issitt R.

Perfusion, 2025

Severe Parvovirus B19-Associated Myocarditis in Children in the Post-COVID-19 Era: A Multicenter Observational Cohort Study.

Russell N., Hatcher J., Best T., Breuer J., Charlesworth J., Muir P., Vipond B., Paulus S., Saxena R., Simmonds J., Vergnano S., Davis P., Kadambari S.

Open forum infectious diseases, 2025

The effect of excessive gas to blood ratios in an ECMO oxygenator.

Shaw M., Cross N., Richardson R., Crook R., Thirulchelvam T., Issitt R.

Perfusion, 2025

Little Journey: a phase III randomised controlled trial of a psychological preparation and education smartphone application for management of paediatric perioperative anxiety compared with standard care in children undergoing ambulatory surgery - study protocol.

Evans C., Bercades G., Ambler G., Wilson M., Brew-Graves C., Baldini C., Begum-Ali N., Williams N., Emberton M., Fenton M., Fancourt D., Samani M., Mythen M., Moonesinghe S.

BMJ open, 2025

Mechanical circulatory support early after pediatric heart transplantation-an analysis from the Pediatric Heart Transplant Society.

Simmonds J., Zangwill S., Wisotzkey B., Cantor R., Zhao H., Kirklin J., Gupta D.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2025

Increasing Number of Clinically Severe Mycoplasma pneumoniae Infections in Children After the COVID-19 Pandemic: A Single-Center Case Series.

McCarthy K., Hatcher J., Best T., Kaliakatsos M., Hassell J., Turnbull A., Sidgwick P., Gavela J., Simmonds J., Kucera F., Warris A., Kadambari S.

Journal of the Pediatric Infectious Diseases Society, 2025

Impact of COVID-19 non-pharmaceutical interventions on bacterial infections in children: an international electronic health record-based study.

Zachariasse J., Gutiérrez-Sacristán A., Makwana S., Li X., Bhatnagar S., Hanauer D., Kainth M., Morris M., Rubio-Mayo P., Sáez C., Shah M., Aronow B., Badenes R., Cai T., Garcia Barrio N., Issitt R., Mandl K., Milani G., Moshal K., Newburger J., Omenn G., Romero-Garcia N., Sperotto F., Spiridou A., Visweswaran S., Xia Z., Bourgeois F., Avillach P.

BMJ public health, 2025

2024

Sacubitril/Valsartan in Pediatric Heart Failure (PANORAMA-HF): A Randomized, Multicenter, Double-Blind Trial.

Shaddy R., Burch M., Kantor P., Solar-Yohay S., Garito T., Zhang S., Kocun M., Mao C., Cilliers A., Wang X., Canter C., Rossano J., Wallis G., Menteer J., Daou L., Kusa J., Tokel K., Dilber D., Xu Z., Xiao T., Halnon N., Daly K., Bock M., Zuckerman W., Singh T., Chakrabarti M., Levitas A., Senni M., Grutter G., Kim G., Song J., Lee H., Chen C., Sanchez-de-Toledo J., Law Y., Wanitkun S., Cui Y., Anjos R., Mese T., Bonnet D.

Circulation, 2024

One- and Two-year Multidisciplinary Follow-Up of MIS-C at a Tertiary Hospital: A Retrospective Cohort Study.

Johnson S., Penner J., Issitt R., Kmentt L., Grant K., Pandey A., Champsas D., Abdel-Mannan O., Maillard S., McKenzie K., Golding E., Kucera F., Hacohen Y., Moshal K.

The Pediatric infectious disease journal, 2024

ABO-incompatible heart transplantation-evolution of a revolution.

Bansal N., West L., Simmonds J., Urschel S.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2024

The European Registry for Patients with Mechanical Circulatory Support (EUROMACS): fourth Paediatric EUROMACS (Paedi-EUROMACS) report.

Rohde S., van Puyvelde J., Veen K., Schweiger M., Biermann D., Amodeo A., Martens T., Damman K., Gollmann-Tepeköylü C., Hulman M., Iacovoni A., Krämer U., Loforte A., Pace Napoleone C., Nemec P., Netuka I., Özbaran M., Polo L., Pya Y., Ramjankhan F., Sandica E., Sliwka J., Stiller B., Kadner A., Franceschini A., Thiruchelvam T., Zimpfer D., Berger F., Davies B., Dashkevich A., Stark C., Meyns B., de By T., Miera O.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2024

Impact of prolonged ischemic time on pediatric heart transplantation outcomes: Improved outcomes in the most recent era.

Auerbach S., Arshad A., Azeka E., Cantor R., Kirklin J., Koehl D., Menteer J., Peng D., Ravekes W., Shaw F., Shih R., Simmonds J., Ballweg J.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2024

Long-term outcome after neonatal intervention for congenital critical aortic stenosis.

Bonello B., Issitt R., Hughes M., Carr M., Iriart X., Khambadkone S., Giardini A., Kostolny M., Marek J.

International journal of cardiology, 2024

Dapagliflozin and Empagliflozin in Paediatric Indications: A Systematic Review.

Lava S., Laurence C., Di Deo A., Sekarski N., Burch M., Della Pasqua O.

Paediatric drugs, 2024

Rapid desensitization through immunoadsorption during cardiopulmonary bypass. A novel method to facilitate human leukocyte antigen incompatible heart transplantation.

Issitt R., Cudworth E., Cortina-Borja M., Gupta A., Kallon D., Crook R., Shaw M., Robertson A., Tsang V., Henwood S., Muthurangu V., Sebire N., Burch M., Fenton M.

Perfusion, 2024

Three decades of collaboration through the Pediatric Heart Transplant Society Registry: A journey through registry data with a highlight on children with single ventricle anatomy.

Richmond M., Conway J., Kirklin J., Cantor R., Koehl D., Lal A., McDonald N., Gajarski R., Lin K., Singh R., Fenton M., Asante-Korang A., Amdani S., Auerbach S., Everitt M.

Pediatric transplantation, 2024

Cardiovascular outcomes improve in children with renovascular hypertension following endovascular and surgical interventions.

Redhead E., Paessler A., Arslan Z., Patel P., Minhas K., Forman C., Hollis P., Lava S., Ionescu F., Manuel D., Ray S., Kessaris N., Giardini A., Ratnamma V., Dobby N., Tullus K., Simmonds J., Stojanovic J.

Pediatric nephrology (Berlin, Germany), 2024

Clinical Outcomes and Quality of Life of Patients Receiving Multi-Solid-Organ Transplants in Childhood Are Excellent: Results From a 20-Year Cohort Study.

Paessler A., Maple H., Cortes M., Simmonds J., Tse Y., Raja M., Muorah M., Kessaris N., Stojanovic J.

Transplant international : official journal of the European Society for Organ Transplantation, 2024

The potential of autologous regulatory T cell (Treg) therapy to prevent Cardiac Allograft Vasculopathy (CAV) in paediatric heart transplant recipients.

Aiyengar A., Romano M., Burch M., Lombardi G., Fanelli G.

Frontiers in immunology, 2024

2023

Immunology of THymectomy And childhood CArdiac transplant (ITHACA): protocol for a UK-wide prospective observational cohort study to identify immunological risk factors of post-transplant lymphoproliferative disease (PTLD) in thymectomised children.

Offor U., Hollis P., Ognjanovic M., Parry G., Khushnood A., Long H., Gennery A., Bacon C., Simmonds J., Reinhardt Z., Bomken S.

BMJ open, 2023

Lung transplantation in an 18-month-old with donor specific antibodies - The use of intraoperative, targeted plasma exchange.

Issitt R., Shetty P., Crook R., Cross N., Henwood S., Broadhead M., Spencer H., Aurora P., Gupta A., Kallon D., Fenton M., Muthialu N.

Perfusion, 2023

Clinical phenotypes and outcomes in children with multisystem inflammatory syndrome across SARS-CoV-2 variant eras: a multinational study from the 4CE consortium.

Sperotto F., Gutiérrez-Sacristán A., Makwana S., Li X., Rofeberg V., Cai T., Bourgeois F., Omenn G., Hanauer D., Sáez C., Bonzel C., Bucholz E., Dionne A., Elias M., García-Barrio N., González T., Issitt R., Kernan K., Laird-Gion J., Maidlow S., Mandl K., Ahooyi T., Moraleda C., Morris M., Moshal K., Pedrera-Jiménez M., Shah M., South A., Spiridou A., Taylor D., Verdy G., Visweswaran S., Wang X., Xia Z., Zachariasse J., Newburger J., Avillach P.

EClinicalMedicine, 2023

Efficacy of outcome prediction of the respiratory ECMO survival prediction score and the predicting death for severe ARDS on VV-ECMO score for patients with acute respiratory distress syndrome on extracorporeal membrane oxygenation.

Majithia-Beet G., Naemi R., Issitt R.

Perfusion, 2023

A national pilot of donation after circulatory death (DCD) heart transplantation within the United Kingdom.

Messer S., Rushton S., Simmonds L., Macklam D., Husain M., Jothidasan A., Large S., Tsui S., Kaul P., Baxter J., Osman M., Mehta V., Russell D., Stock U., Dunning J., Saez D., Venkateswaran R., Curry P., Ayton L., Mukadam M., Mascaro J., Simmonds J., Macgowan G., Clark S., Jungschleger J., Reinhardt Z., Quigley R., Speed J., Parameshwar J., Jenkins D., Watson S., Marley F., Ali A., Gardiner D., Rubino A., Whitney J., Beale S., Slater C., Currie I., Armstrong L., Foley J., Ryan M., Gibson S., Quinn K., Macleod A., Spence S., Watson C., Catarino P., Clarkson A., Forsythe J., Manas D., Berman M.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2023

Oxygen delivery in pediatric cardiac surgery and its association with acute kidney injury using machine learning.

Hayward A., Robertson A., Thiruchelvam T., Broadhead M., Tsang V., Sebire N., Issitt R.

The Journal of thoracic and cardiovascular surgery, 2023

Baseline Characteristics of Pediatric Patients With Heart Failure Due to Systemic Left Ventricular Systolic Dysfunction in the PANORAMA-HF Trial.

Shaddy R., Burch M., Kantor P., Solar-Yohay S., Garito T., Zhang S., Kocun M., Bonnet D.

Circulation. Heart failure, 2023

2022

Outcomes in small children on Berlin Heart EXCOR support: age and body surface area as clinical predictive factors.

Rohde S., Sandica E., Veen K., Kraemer U., Thiruchelvam T., Miera O., Lopez M., Sliwka J., Amodeo A., Bogers A., de By T.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2022

Clinical approach to antibody-mediated rejection from the pediatric heart transplant society.

Amdani S., Henderson H., Everitt M., Beasley G., Shih R., Exil V., Alejos J., Wallis G., Azeka E., Nandi D., Profita E., Spinner J., Magnetta D., Martinez H., Fenton M., Conway J., Urschel S.

Pediatric transplantation, 2022

Cardiac care of children with dystrophinopathy and females carrying DMD-gene variations.

Bourke J., Turner C., Bradlow W., Chikermane A., Coats C., Fenton M., Ilina M., Johnson A., Kapetanakis S., Kuhwald L., Morley-Davies A., Quinlivan R., Savvatis K., Schiava M., Yousef Z., Guglieri M.

Open heart, 2022

Presentation of cardiogenic shock with pulmonary hypertension and arrhythmia secondary to foramen magnum stenosis in a patient with achondroplasia.

Gavela J., Sharma S., Thompson D., Cocca A., Thiruchelvam T., Moledina S.

Journal of paediatrics and child health, 2022

Cardiac outcomes in severe acute respiratory syndrome coronavirus-2-associated multisystem inflammatory syndrome at a tertiary paediatric hospital.

Kucera F., Laurence C., Simmonds J., Gavela J., Bodnar T., Brogan P., Hoskote A., Skellett S., Moshal K., Bamford A., Khambadkone S.

Cardiology in the young, 2022

Daratumumab provides transient response of antibody mediated rejection post pediatric orthotopic heart transplantation.

Fenton M., Shaw K., Murchan H., Duignan S., Dunne E., McMahon C.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2022

Exploring the Possible Impact of Echocardiographic Diastolic Function Parameters on Outcome in Paediatric Dilated Cardiomyopathy.

Bressieux-Degueldre S., Fenton M., Dominguez T., Burch M.

Children (Basel, Switzerland), 2022

Cerebrovascular accidents in paediatric patients supported by the Berlin Heart EXCOR.

Rohde S., Sandica E., Veen K., Miera O., Amodeo A., Napoleone C., Özbaran M., Sliwka J., Thiruchelvam T., Zimpfer D., Schubert S., Bogers A., de By T.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2022

Extracorporeal membrane oxygenation after the Norwood operation: making the best of a tough situation.

Brown K., Thiruchelvam T., Kostolny M.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2022

Pediatric heart transplantation following donation after circulatory death, distant procurement, and ex-situ perfusion.

Laurence C., Nachum E., Henwood S., Berman M., Large S., Messer S., Kaul P., Baxter J., Quigley R., Osman M., Muthialu N., Davies B., Bohuta L., Kostolny M., Burch M., Fenton M., Andrews R., Thiruchelvam T., Hoskote A., Simmonds J.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2022

The European Registry for Patients with Mechanical Circulatory Support (EUROMACS): third Paediatric (Paedi-EUROMACS) report.

de By T., Schweiger M., Hussain H., Amodeo A., Martens T., Bogers A., Damman K., Gollmann-Tepeköylü C., Hulman M., Iacovoni A., Krämer U., Loforte A., Napoleone C., Němec P., Netuka I., Özbaran M., Polo L., Pya Y., Ramjankhan F., Sandica E., Sliwka J., Stiller B., Kadner A., Franceschini A., Thiruchelvam T., Zimpfer D., Meyns B., Berger F., Miera O.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2022

International comparisons of laboratory values from the 4CE collaborative to predict COVID-19 mortality.

Weber G., Hong C., Xia Z., Palmer N., Avillach P., L'Yi S., Keller M., Murphy S., Gutiérrez-Sacristán A., Bonzel C., Serret-Larmande A., Neuraz A., Omenn G., Visweswaran S., Klann J., South A., Loh N., Cannataro M., Beaulieu-Jones B., Bellazzi R., Agapito G., Alessiani M., Aronow B., Bell D., Benoit V., Bourgeois F., Chiovato L., Cho K., Dagliati A., DuVall S., Barrio N., Hanauer D., Ho Y., Holmes J., Issitt R., Liu M., Luo Y., Lynch K., Maidlow S., Malovini A., Mandl K., Mao C., Matheny M., Moore J., Morris J., Morris M., Mowery D., Ngiam K., Patel L., Pedrera-Jimenez M., Ramoni R., Schriver E., Schubert P., Balazote P., Spiridou A., Tan A., Tan B., Tibollo V., Torti C., Trecarichi E., Wang X., Kohane I., Cai T., Brat G.

NPJ digital medicine, 2022

Post-transplant lymphoproliferative disorder presenting as supraglottitis following pediatric heart transplantation treated with EBV-specific cytotoxic T-lymphocytes.

Duignan S., O'Marcaigh A., Russell J., Mehanna R., McDermott M., Fenton M., McMahon C.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2022

Hepatorenal dysfunction assessment with the Model for End-Stage Liver Disease Excluding INR score predicts worse survival after heart transplant in pediatric Fontan patients.

Amdani S., Simpson K., Thrush P., Shih R., Simmonds J., Knecht K., Mogul D., Hurley K., Koehl D., Cantor R., Naftel D., Kirklin J., Daly K.

The Journal of thoracic and cardiovascular surgery, 2022

Classification Performance of Neural Networks Versus Logistic Regression Models: Evidence From Healthcare Practice.

Issitt R., Cortina-Borja M., Bryant W., Bowyer S., Taylor A., Sebire N.

Cureus, 2022

2021

Clinical and hemodynamic characteristics of the pediatric failing Fontan.

Dykes J., Rosenthal D., Bernstein D., McElhinney D., Chrisant M., Daly K., Ameduri R., Knecht K., Richmond M., Lin K., Urschel S., Simmonds J., Simpson K., Albers E., Khan A., Schumacher K., Almond C., Chen S.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2021

Intraoperative anti-A/B immunoadsorption is associated with significantly reduced blood product utilization with similar outcomes in pediatric ABO-incompatible heart transplantation.

Issitt R., Booth J., Crook R., Robertson A., Molyneux V., Richardson R., Cross N., Shaw M., Tsang V., Muthurangu V., Sebire N., Burch M., Fenton M.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2021

Epstein-Barr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV.

Venturini C., Houldcroft C., Lazareva A., Wegner F., Morfopoulou S., Amrolia P., Golwala Z., Rao A., Marks S., Simmonds J., Yoshikawa T., Farrell P., Cohen J., Worth A., Breuer J.

British journal of haematology, 2021

Learning networks in pediatric heart failure and transplantation.

O'Connor M., Lorts A., Kwiatkowski D., Butts R., Barnes A., Jeewa A., Knoll C., Fenton M., McQueen M., Cousino M., Shugh S., Rosenthal D.

Pediatric transplantation, 2021

T cell phenotype in paediatric heart transplant recipients.

Mengrelis K., Kucera F., Shahid N., Watt E., Ross S., Lau C., Adams S., Gilmour K., Pils D., Crompton T., Burch M., Davies E.

Pediatric transplantation, 2021

Isolation and expansion of thymus-derived regulatory T cells for use in pediatric heart transplant patients.

Romano M., Sen M., Scottà C., Alhabbab R., Rico-Armada A., Lechler R., Burch M., Lombardi G.

European journal of immunology, 2021

International Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries.

Bourgeois F., Gutiérrez-Sacristán A., Keller M., Liu M., Hong C., Bonzel C., Tan A., Aronow B., Boeker M., Booth J., Cruz Rojo J., Devkota B., García Barrio N., Gehlenborg N., Geva A., Hanauer D., Hutch M., Issitt R., Klann J., Luo Y., Mandl K., Mao C., Moal B., Moshal K., Murphy S., Neuraz A., Ngiam K., Omenn G., Patel L., Jiménez M., Sebire N., Balazote P., Serret-Larmande A., South A., Spiridou A., Taylor D., Tippmann P., Visweswaran S., Weber G., Kohane I., Cai T., Avillach P.

JAMA network open, 2021

Blood group-incompatible heart transplantation in children-an idea worth spreading.

Fenton M.

The Lancet. Child & adolescent health, 2021

Cone reconstruction for Ebstein anomaly: Late biventricular function and possible remodeling.

Neijenhuis R., Tsang V., Marek J., Issitt R., Bonello B., Von Klemperer K., Hughes M.

The Journal of thoracic and cardiovascular surgery, 2021

Critical paediatric COVID-19: varied presentations but good outcomes.

Lanyon N., du Pré P., Thiruchelvam T., Ray S., Johnson M., Peters M.

Archives of disease in childhood, 2021

International Comparisons of Harmonized Laboratory Value Trajectories to Predict Severe COVID-19: Leveraging the 4CE Collaborative Across 342 Hospitals and 6 Countries: A Retrospective Cohort Study.

Weber G., Hong C., Palmer N., Avillach P., Murphy S., Gutiérrez-Sacristán A., Xia Z., Serret-Larmande A., Neuraz A., Omenn G., Visweswaran S., Klann J., South A., Loh N., Cannataro M., Beaulieu-Jones B., Bellazzi R., Agapito G., Alessiani M., Aronow B., Bell D., Bellasi A., Benoit V., Beraghi M., Boeker M., Booth J., Bosari S., Bourgeois F., Brown N., Bucalo M., Chiovato L., Chiudinelli L., Dagliati A., Devkota B., DuVall S., Follett R., Ganslandt T., García Barrio N., Gradinger T., Griffier R., Hanauer D., Holmes J., Horki P., Huling K., Issitt R., Jouhet V., Keller M., Kraska D., Liu M., Luo Y., Lynch K., Malovini A., Mandl K., Mao C., Maram A., Matheny M., Maulhardt T., Mazzitelli M., Milano M., Moore J., Morris J., Morris M., Mowery D., Naughton T., Ngiam K., Norman J., Patel L., Pedrera Jimenez M., Ramoni R., Schriver E., Scudeller L., Sebire N., Serrano Balazote P., Spiridou A., Tan A., Tan B., Tibollo V., Torti C., Trecarichi E., Vitacca M., Zambelli A., Zucco C., Kohane I., Cai T., Brat G.

medRxiv : the preprint server for health sciences, 2021

Machine Learning Approaches to Determine Feature Importance for Predicting Infant Autopsy Outcome.

Booth J., Margetts B., Bryant W., Issitt R., Hutchinson C., Martin N., Sebire N.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 2021

The Great Ormond Street Hospital immunoadsorption method for ABO-incompatible heart transplantation: a practical technique.

Issitt R., Crook R., Shaw M., Robertson A.

Perfusion, 2021

Fourth ventricle tumors in children: complications and influence of surgical approach.

Toescu S., Samarth G., Layard Horsfall H., Issitt R., Margetts B., Phipps K., Jeelani N., Thompson D., Aquilina K.

Journal of neurosurgery. Pediatrics, 2021

2020

Endomyocardial Biopsy in a Pediatric Patient With Cardiac Manifestations of COVID-19.

Laurence C., Haini M., Thiruchelvam T., Derrick G., Burch M., Yates R., Simmonds J.

Circulation. Heart failure, 2020

Surveillance for cardiac allograft vasculopathy: Practice variations among 50 pediatric heart transplant centers.

Nandi D., Chin C., Schumacher K., Fenton M., Singh R., Lin K., Conway J., Cantor R., Koehl D., Lamour J., Kirklin J., Pahl E.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2020

The impact of home hemodialysis in children with severe cardiac failure.

Hothi D., Fenton M.

Hemodialysis international. International Symposium on Home Hemodialysis, 2020

Extracorporeal Cardiopulmonary Resuscitation: So Many Questions, How Much Time Have You Got?

Brown K., Thiruchelvam T.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2020

Cardiorespiratory Progression Over 5 Years and Role of Corticosteroids in Duchenne Muscular Dystrophy: A Single-Site Retrospective Longitudinal Study.

Trucco F., Domingos J., Tay C., Ridout D., Maresh K., Munot P., Sarkozy A., Robb S., Quinlivan R., Riley M., Burch M., Fenton M., Wallis C., Chan E., Abel F., Manzur A., Muntoni F.

Chest, 2020

Cell-Free DNA in Pediatric Solid Organ Transplantation Using a New Detection Method of Separating Donor-Derived from Recipient Cell-Free DNA.

Preka E., Ellershaw D., Chandler N., Ahlfors H., Spencer H., Chitty L., Fenton M., Marks S.

Clinical chemistry, 2020

The complication rate of intravascular ultrasound (IVUS) in a multicenter pediatric heart transplant population: A study of the international pediatric IVUS consortium.

Auerbach S., Fenton M., Grutter G., Albert D., Di-Filippo S., Burch M., Kuhn M.

Clinical transplantation, 2020

Children with COVID-19 at a specialist centre: initial experience and outcome.

Issitt R., Booth J., Bryant W., Spiridou A., Taylor A., du Pré P., Ramnarayan P., Hartley J., Cortina-Borja M., Moshal K., Dunn H., Hemingway H., Sebire N.

The Lancet. Child & adolescent health, 2020

Cardiopulmonary Bypass for a Patient With Congenital Hyperinsulinemia.

Crook R., Issitt R.

World journal for pediatric & congenital heart surgery, 2020

The utility of aortic valve leaflet reconstruction techniques in children and young adults.

Wiggins L., Mimic B., Issitt R., Ilic S., Bonello B., Marek J., Kostolny M.

The Journal of thoracic and cardiovascular surgery, 2020

Prioritising transplantation for adult congenital heart disease, UK national data.

Burch M., Taylor A., Mehew J., Dominguez T., Crossland D., Lewis C., Taylor R., Clift P., Al-Attar N., Venkateswaran R., Banner N.

International journal of cardiology, 2020

Review of the impact of donor characteristics on pediatric heart transplant outcomes.

Conway J., Ballweg J., Fenton M., Kindel S., Chrisant M., Weintraub R., Danziger-Isakov L., Kirk R., Meira O., Davies R., Dipchand A.

Pediatric transplantation, 2020

Melody Valve in Aortic Position to Facilitate Mechanical Circulatory Support as a Bridge to Cardiac Transplantation.

Khambadkone S., Burch M., Fenton M., Derrick G., Thiruchelvam T., Karimova A., Bohuta L., Hsia T.

The Annals of thoracic surgery, 2020

ISHLT consensus statement on donor organ acceptability and management in pediatric heart transplantation.

Kirk R., Dipchand A., Davies R., Miera O., Chapman G., Conway J., Denfield S., Gossett J., Johnson J., McCulloch M., Schweiger M., Zimpfer D., Ablonczy L., Adachi I., Albert D., Alexander P., Amdani S., Amodeo A., Azeka E., Ballweg J., Beasley G., Böhmer J., Butler A., Camino M., Castro J., Chen S., Chrisant M., Christen U., Danziger-Isakov L., Das B., Everitt M., Feingold B., Fenton M., Garcia-Guereta L., Godown J., Gupta D., Irving C., Joong A., Kemna M., Khulbey S., Kindel S., Knecht K., Lal A., Lin K., Lord K., Möller T., Nandi D., Niesse O., Peng D., Pérez-Blanco A., Punnoose A., Reinhardt Z., Rosenthal D., Scales A., Scheel J., Shih R., Smith J., Smits J., Thul J., Weintraub R., Zangwill S., Zuckerman W.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2020

2019

Donation after circulatory death in lung transplantation-five-year follow-up from ISHLT Registry.

Van Raemdonck D., Keshavjee S., Levvey B., Cherikh W., Snell G., Erasmus M., Simon A., Glanville A., Clark S., D'Ovidio F., Catarino P., McCurry K., Hertz M., Venkateswaran R., Hopkins P., Inci I., Walia R., Kreisel D., Mascaro J., Dilling D., Camp P., Mason D., Musk M., Burch M., Fisher A., Yusen R., Stehlik J., Cypel M.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2019

Pediatric heart transplantation in the current era.

D'Addese L., Joong A., Burch M., Pahl E.

Current opinion in pediatrics, 2019

Systematic literature review on the economic, humanistic, and societal burden of heart failure in children and adolescents.

Burch M., Nallagangula T., Nic Lochlainn E., Severin T., Thakur L., Jaecklin T., George A., Solar-Yohay S., Rossano J., Shaddy R.

Expert review of pharmacoeconomics & outcomes research, 2019

Permanent pacemaker implantation after pediatric heart transplantation: Risk factors, indications, and outcomes.

Mahmood A., Andrews R., Fenton M., Morrison A., Mangat J., Davies B., Burch M., Simmonds J.

Clinical transplantation, 2019

2018

Recommendations from the Association for European Paediatric and Congenital Cardiology for clinical training in paediatric heart failure and transplantation.

Reinhardt Z., Hansmann G., O'Sullivan J., Murtuza B., Köstenberger M., Schranz D., Bonnet D., Burch M.

Cardiology in the young, 2018

Potential for and timing of recovery in children with dilated cardiomyopathy.

Fenton M., Horne P., Simmonds J., Neligan S., Andrews R., Burch M.

International journal of cardiology, 2018

Specific Immunity to Cytomegalovirus in Pediatric Cardiac Transplantation.

Jacobsen M., Manunta M., Pincott E., Fenton M., Simpson G., Klein N., Burch M.

Transplantation, 2018

The importance of qualitative and quantitative regional wall motion abnormality assessment at rest in pediatric coronary allograft vasculopathy.

Dedieu N., Silva Vieira M., Fenton M., Wong J., Botnar R., Burch M., Greil G., Hussain T.

Pediatric transplantation, 2018

A novel method for ABO-incompatible heart transplantation.

Robertson A., Issitt R., Crook R., Gustafsson K., Eddaoudi A., Tsang V., Burch M.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2018

Development and validation of a major adverse transplant event (MATE) score to predict late graft loss in pediatric heart transplantation.

Almond C., Hoen H., Rossano J., Castleberry C., Auerbach S., Yang L., Lal A., Everitt M., Fenton M., Hollander S., Pahl E., Pruitt E., Rosenthal D., McElhinney D., Daly K., Desai M.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2018

Transplanted human thymus slices induce and support T-cell development in mice after cryopreservation.

Ross S., Cheung M., Lau C., Sebire N., Burch M., Kilbride P., Fuller B., Morris G., Davies E., Crompton T.

European journal of immunology, 2018

Beta-thalassemia in the paediatric cardiac surgery setting - a case report and literature review.

Richardson R., Issitt R., Crook R.

Perfusion, 2018

Systematic Literature Review on the Incidence and Prevalence of Heart Failure in Children and Adolescents.

Shaddy R., George A., Jaecklin T., Lochlainn E., Thakur L., Agrawal R., Solar-Yohay S., Chen F., Rossano J., Severin T., Burch M.

Pediatric cardiology, 2018

Question 1: How safe are ACE inhibitors for heart failure in children?

van der Meulen M., Dalinghaus M., Burch M., Szatmari A., Castro Diez C., Khalil F., Swoboda V., Breur J., Bajcetic M., Jovanovic I., Lagler F., Klingmann I., Laeer S., de Wildt S.

Archives of disease in childhood, 2018

2017

Design for the sacubitril/valsartan (LCZ696) compared with enalapril study of pediatric patients with heart failure due to systemic left ventricle systolic dysfunction (PANORAMA-HF study).

Shaddy R., Canter C., Halnon N., Kochilas L., Rossano J., Bonnet D., Bush C., Zhao Z., Kantor P., Burch M., Chen F.

American heart journal, 2017

Leukocyte filtration of the cardiotomy suction. Does it affect systemic leukocyte activation or pulmonary function?

Issitt R., Ball J., Bilkhoo I., Mani A., Walsh B., Voegeli D.

Perfusion, 2017

Do lipid microemboli induce acute kidney injury during cardiopulmonary bypass?

Issitt R., James T., Walsh B., Voegeli D.

Perfusion, 2017

Quantification of Lipid Filtration and the Effects on Cerebral Injury During Cardiopulmonary Bypass.

Issitt R., Harvey I., Walsh B., Voegeli D.

The Annals of thoracic surgery, 2017

Clinical practice patterns are relatively uniform between pediatric heart transplant centers: A survey-based assessment.

Castleberry C., Ziniel S., Almond C., Auerbach S., Hollander S., Lal A., Fenton M., Pahl E., Rossano J., Everitt M., Daly K.

Pediatric transplantation, 2017

A randomized study of autologous bone marrow-derived stem cells in pediatric cardiomyopathy.

Pincott E., Ridout D., Brocklesby M., McEwan A., Muthurangu V., Burch M.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2017

Oncotic pressure and paediatric cardiopulmonary bypass: establishing baseline data for complex congenital cardiac surgery and its relation to risk stratification.

Crook R., Issitt R.

Perfusion, 2017

Meta-Analysis of the Effectiveness of Heart Transplantation in Patients With a Failing Fontan.

Tabarsi N., Guan M., Simmonds J., Toma M., Kiess M., Tsang V., Ruygrok P., Konstantinov I., Shi W., Grewal J.

The American journal of cardiology, 2017

Calcineurin inhibitor-free immunosuppression.

Simmond J., Burch M.

Pediatric transplantation, 2017

Assessment of Diastolic Function in Congenital Heart Disease.

Panesar D., Burch M.

Frontiers in cardiovascular medicine, 2017

2016

A multi-institutional evaluation of antibody-mediated rejection utilizing the Pediatric Heart Transplant Study database: Incidence, therapies and outcomes.

Thrush P., Pahl E., Naftel D., Pruitt E., Everitt M., Missler H., Zangwill S., Burch M., Hoffman T., Butts R., Mahle W.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2016

Diagnostic performance and reference values of novel biomarkers of paediatric heart failure.

Hauser J., Demyanets S., Rusai K., Goritschan C., Weber M., Panesar D., Rindler L., Taylor A., Marculescu R., Burch M., Wojta J., Michel-Behnke I.

Heart (British Cardiac Society), 2016

Invited Commentary on: Effect of cardiopulmonary bypass on platelet mitochondrial respiration and correlation with aggregation and bleeding: a pilot study.

Issitt R.

Perfusion, 2016

Eosinophilic granulomatosis with polyangiitis in childhood: retrospective experience from a tertiary referral centre in the UK.

Eleftheriou D., Gale H., Pilkington C., Fenton M., Sebire N., Brogan P.

Rheumatology (Oxford, England), 2016

Heart failure from heart muscle disease in childhood: a 5-10 year follow-up study in the UK and Ireland.

Andrews R., Fenton M., Dominguez T., Burch M.

ESC heart failure, 2016

An unusual case of left bronchial compression caused by a large patent arterial duct in a child with pulmonary atresia with ventricular septal defect.

Mimic B., Tsang V., Owens C., Thiruchelvam T., Kostolny M.

European heart journal. Cardiovascular Imaging, 2016

Pathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veins.

Szafranski P., Gambin T., Dharmadhikari A., Akdemir K., Jhangiani S., Schuette J., Godiwala N., Yatsenko S., Sebastian J., Madan-Khetarpal S., Surti U., Abellar R., Bateman D., Wilson A., Markham M., Slamon J., Santos-Simarro F., Palomares M., Nevado J., Lapunzina P., Chung B., Wong W., Chu Y., Mok G., Kerem E., Reiter J., Ambalavanan N., Anderson S., Kelly D., Shieh J., Rosenthal T., Scheible K., Steiner L., Iqbal M., McKinnon M., Hamilton S., Schlade-Bartusiak K., English D., Hendson G., Roeder E., DeNapoli T., Littlejohn R., Wolff D., Wagner C., Yeung A., Francis D., Fiorino E., Edelman M., Fox J., Hayes D., Janssens S., De Baere E., Menten B., Loccufier A., Vanwalleghem L., Moerman P., Sznajer Y., Lay A., Kussmann J., Chawla J., Payton D., Phillips G., Brosens E., Tibboel D., de Klein A., Maystadt I., Fisher R., Sebire N., Male A., Chopra M., Pinner J., Malcolm G., Peters G., Arbuckle S., Lees M., Mead Z., Quarrell O., Sayers R., Owens M., Shaw-Smith C., Lioy J., McKay E., de Leeuw N., Feenstra I., Spruijt L., Elmslie F., Thiruchelvam T., Bacino C., Langston C., Lupski J., Sen P., Popek E., Stankiewicz P.

Human genetics, 2016

Parvovirus B19 myocarditis in children: an observational study.

Vigneswaran T., Brown J., Breuer J., Burch M.

Archives of disease in childhood, 2016

Detection of Low Frequency Multi-Drug Resistance and Novel Putative Maribavir Resistance in Immunocompromised Pediatric Patients with Cytomegalovirus.

Houldcroft C., Bryant J., Depledge D., Margetts B., Simmonds J., Nicolaou S., Tutill H., Williams R., Worth A., Marks S., Veys P., Whittaker E., Breuer J.

Frontiers in microbiology, 2016

2015

Changes in health in England, with analysis by English regions and areas of deprivation, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

Newton J., Briggs A., Murray C., Dicker D., Foreman K., Wang H., Naghavi M., Forouzanfar M., Ohno S., Barber R., Vos T., Stanaway J., Schmidt J., Hughes A., Fay D., Ecob R., Gresser C., McKee M., Rutter H., Abubakar I., Ali R., Anderson H., Banerjee A., Bennett D., Bernabé E., Bhui K., Biryukov S., Bourne R., Brayne C., Bruce N., Brugha T., Burch M., Capewell S., Casey D., Chowdhury R., Coates M., Cooper C., Critchley J., Dargan P., Dherani M., Elliott P., Ezzati M., Fenton K., Fraser M., Fürst T., Greaves F., Green M., Gunnell D., Hannigan B., Hay R., Hay S., Hemingway H., Larson H., Looker K., Lunevicius R., Lyons R., Marcenes W., Mason-Jones A., Matthews F., Moller H., Murdoch M., Newton C., Pearce N., Piel F., Pope D., Rahimi K., Rodriguez A., Scarborough P., Schumacher A., Shiue I., Smeeth L., Tedstone A., Valabhji J., Williams H., Wolfe C., Woolf A., Davis A.

Lancet (London, England), 2015

Improved Detection of Cardiac Allograft Vasculopathy: A Multi-Institutional Analysis of Functional Parameters in Pediatric Heart Transplant Recipients.

Kindel S., Law Y., Chin C., Burch M., Kirklin J., Naftel D., Pruitt E., Carboni M., Arens A., Atz A., Dreyer W., Mahle W., Pahl E.

Journal of the American College of Cardiology, 2015

Outcome of shared care for pediatric cardiac transplantation between two nations with different health care systems.

Simmonds J., Murchan H., James A., Crispino G., O'Brien J., Crumlish K., Franklin O., Fenton M., Burch M., McMahon C.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2015

Predictors and Outcome of Extracorporeal Life Support After Pediatric Heart Transplantation.

Simmonds J., Dominguez T., Longman J., Shastri N., O'Callaghan M., Hoskote A., Fenton M., Burch M., Tsang V., Brown K.

The Annals of thoracic surgery, 2015

2014

Diagnosis and management of coronary allograft vasculopathy in children and adolescents.

Dedieu N., Greil G., Wong J., Fenton M., Burch M., Hussain T.

World journal of transplantation, 2014

The International Society for Heart and Lung Transplantation Guidelines for the management of pediatric heart failure: Executive summary. [Corrected].

Kirk R., Dipchand A., Rosenthal D., Addonizio L., Burch M., Chrisant M., Dubin A., Everitt M., Gajarski R., Mertens L., Miyamoto S., Morales D., Pahl E., Shaddy R., Towbin J., Weintraub R.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2014

New 15-mL ventricular assist device in children with restrictive physiology of the left ventricle.

Sundararajan S., Thiruchelvam T., Hsia T., Karimova A.

The Journal of thoracic and cardiovascular surgery, 2014

2013

Almanac 2012: congenital heart disease. The journals present selected research that has driven recent advances in clinical cardiology.

Burch M., Dedieu N.

Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2013

Almanac 2012: congenital heart disease. The national society journals present selected research that has driven recent advances in clinical cardiology.

Burch M., Dedieu N.

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2013

Almanac 2012: Congenital heart disease.

Burch M., Dedieu N.

Archivos de cardiologia de Mexico, 2013

2012

Congenital heart disease: the national society journals present selected research that has driven recent advances in clinical cardiology.

Burch M., Dedieu N.

Heart (British Cardiac Society), 2012

2011

Invited commentary.

Issitt R.

The Annals of thoracic surgery, 2011

2010

Long-term steroid treatment and growth: a study in steroid-dependent nephrotic syndrome.

Simmonds J., Grundy N., Trompeter R., Tullus K.

Archives of disease in childhood, 2010

2009

Tacrolimus in pediatric heart transplantation: ameliorated side effects in the steroid-free, statin era.

Simmonds J., Dewar C., Dawkins H., Burch M., Fenton M.

Clinical transplantation, 2009

2008

Heart transplantation after congenital heart surgery: improving results and future goals.

Simmonds J., Burch M., Dawkins H., Tsang V.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2008

Successful heart transplantation following neonatal necrotic enterovirus myocarditis.

Simmonds J., Cubitt D., Ashworth M., Burch M.

Pediatric cardiology, 2008

Endothelial dysfunction and cytomegalovirus replication in pediatric heart transplantation.

Simmonds J., Fenton M., Dewar C., Ellins E., Storry C., Cubitt D., Deanfield J., Klein N., Halcox J., Burch M.

Circulation, 2008

2007

Understanding chronic heart failure.

Fenton M., Burch M.

Archives of disease in childhood, 2007

2006

2005

A Dobutamine paradox: eosinophilic myocarditis in the explanted heart of a 9-year-old girl undergoing cardiac transplantation.

Fenton M., Burch M., Sebire N.

Cardiology in the young, 2005

2004

2003

2002

Heart failure in the young.

Burch M.

Heart (British Cardiac Society), 2002