Bloomsbury Centre for Clinical Phenotyping

2025


Metabolic Markers of Mortality Risk in Patients With Severe Aortic Stenosis Undergoing Valve Replacement.

Nitsche C., Thornton G., Bennett J., Gama F., Chadalavadha S., Chaturvedi N., Tillin T., Manisty C., González A., Levelt E., Moon J., Hughes A., Bhuva A., Treibel T.

The American journal of cardiology, 2025


Cerebral blood flow in a tri-ethnic population: insights from pCASL perfusion MRI.

Rehwald R., Sokolska M., Sudre C., Smith L., Tillin T., Atkinson D., Chaturvedi N., Hughes A., Jäger H.

European radiology, 2025


Imaging cardiac fat by cardiovascular magnetic resonance - A state-of-the art review.

Morselli F., Pierce I., Webber M., Falconer D., Hughes A., Orini M., Lambiase P., Moon J., Captur G.

Magnetic resonance imaging, 2025


Myocardial remodelling in aortic regurgitation: time to think beyond volumes and function?

Thornton G., McKenna M., Bennett J., Hughes A., González A., Khanji M., Cavalcante J., Lloyd G., Moon J., Bhattacharyya S., Treibel T.

European heart journal. Cardiovascular Imaging, 2025


Higher Life-Course Blood Pressure Associates With Reduced Myocardial Perfusion in Older Age: Insights From MyoFit46.

Topriceanu C., Webber M., Shiwani H., Chan F., Martin E., Falconer D., Stanley M., Bennett J., Gonzalez-Martin P., Shah H., De S., Wong A., Pierce I., Davies R., Lambiase P., Chaturvedi N., Kellman P., Hardy R., Moon J., Hughes A., Captur G.

Circulation. Cardiovascular imaging, 2025


Comment on Agbaje et al. Persistent Hyperglycemia and Insulin Resistance With the Risk of Worsening Cardiac Damage in Adolescents: A 7-Year Longitudinal Study of the ALSPAC Birth Cohort. Diabetes Care 2025;48:896-904.

Chiesa S., Jones S., Hughes A., Katsoulis M.

Diabetes care, 2025


The socioeconomic trajectories followed during early adulthood contribute to inequalities in cardiometabolic health by age 24 years.

Winpenny E., Stochl J., Hughes A., Tilling K., Howe L.

Social science & medicine (1982), 2025


Accelerated vascular ageing after COVID-19 infection: the CARTESIAN study.

Bruno R., Badhwar S., Abid L., Agharazii M., Anastasio F., Bellien J., Burghuber O., Faconti L., Filipovsky J., Ghiadoni L., Giannattasio C., Hametner B., Hughes A., Jeroncic A., Ikonomidis I., Lonnebakken M., Maloberti A., Mayer C., Muiesan M., Paini A., Panayiotou A., Park C., Rajkumar C., Becerra C., Spronck B., Terentes-Printzios D., Tuncok Y., Weber T., Boutouyrie P.

European heart journal, 2025


Fully automated measurement of aortic pulse wave velocity from routine cardiac MRI studies.

Jiang Y., Yao T., Paliwal N., Knight D., Punjabi K., Steeden J., Hughes A., Muthurangu V., Davies R.

Magnetic resonance imaging, 2025


Systolic BP Amplification: Systematic Review and Individual Participant Meta-Analysis.

Picone D., Bui T., Schultz M., Otahal P., Hughes A., Black J., Westerhof B., Chen C., Liang F., Pucci G., Cheng H., Adams H., Wang J., Dwyer N., Roberts-Thomson P., Goupil R., Paleri S., Eaves S., Peng X., Sharman J.

Hypertension (Dallas, Tex. : 1979), 2025


Periodontitis treatment and progression of carotid intima-media thickness: a randomized trial.

Orlandi M., Masi S., Lucenteforte E., Bhowruth D., Malanima M., Darbar U., Patel K., Lim C., Curra C., Shiehfung T., Suvan J., Chiesa S., Deanfield J., D'Aiuto F.

European heart journal, 2025


Strategies to enhance recruitment of female participants to cardiovascular research: a joint British Cardiovascular Societies' consensus document in collaboration with the British Heart Foundation Clinical Research Collaborative.

Kunadian V., Pompei G., Dasgupta I., Swift P., Adamson D., Banerjee A., Guzik T., Hildick-Smith D., Garbi M., Laskar N., Anderson L., Zakeri R., Ahmed F., Rosen S., Bannister C., Roberts E., Quail M., Coats L., Page S., Wicks E., Moorjani N., Loubani M., Probert H., Cowie A., Thakkar R., Moore J., Deshpande A., Augustine D., Paton M., Captur G., Singh A., Morgan H., Brown O., Ting F., Hogan S., Sanders K., Ashton J., Malkin R., Brown S., Arnold A., Rodas M., Zhecheva V., Ng G.

Heart (British Cardiac Society), 2025


Device-Measured Sleep Characteristics, Daily Step Count, and Cardiometabolic Health Markers: Findings From the Prospective Physical Activity, Sitting, and Sleep (ProPASS) Consortium.

Bian W., Ahmadi M., Biswas R., Blodgett J., Atkin A., Chan H., Del Pozo Cruz B., Suorsa K., Bakker E., Pulsford R., Mielke G., Johansson P., Hettiarachchi P., Koemel N., Thijssen D., Stenholm S., Mishra G., Teixeira-Pinto A., Rangul V., Sherar L., Ekelund U., Hughes A., Lee I., Cistulli P., Holtermann A., Koster A., Hamer M., Stamatakis E.

Circulation. Cardiovascular quality and outcomes, 2025


Social determinants of dementia: A scoping review.

Walsh S., Klee M., Hui E., Saeed U., Waters S., Kuhn I., Siette J., Orgeta V., Stafford J., Smith L., Tamburin S., Jensen D., Mantovani E., Chandra A., James S., Tang E., Llewellyn D., Foote I., Chiesa S., Geraets A.

Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025


Validation of a popular consumer-grade cuffless blood pressure device for continuous 24 h monitoring.

Bhatt B., Amir H., Jones S., Jamieson A., Chaturvedi N., Hughes A., Orini M.

European heart journal. Digital health, 2025


Cohort profile: characterisation, determinants, mechanisms and consequences of the long-term effects of COVID-19 - providing the evidence base for health care services (CONVALESCENCE) in the UK.

Jamieson A., Saikhan L., Raman B., Alghamdi L., Cheetham N., Conde P., Dobson R., Fernández-Sanlés A., Folarin A., Goudswaard L., Hamill Howes L., Jones S., Neubauer S., Orini M., Pierce I., Ranjan Y., Rapala A., Smith S., Sudre C., Thompson E., Wild J., Williams D., Wong A., Steves C., Timpson N., Chaturvedi N., Hughes A.

BMJ open, 2025


Associations of aortic and carotid artery health with cerebrovascular markers and cognition in older adults from the Whitehall II imaging study.

Hobden G., Reid G., Chiesa S., Wang C., Jobbins L., Mackay C., Hughes A., Ebmeier K., Pitt J., Kivimäki M., Singh-Manoux A., Suri S.

BMC medicine, 2025


The Cardiovascular Magnetic Resonance Phenotype of Lamin Heart Disease.

Topriceanu C., Al-Farih M., Joy G., Chan F., Webber M., Ilie-Ablachim D., Shiwani H., Tamang M., Banks C., Pettit S., Petersen S., O'Brien B., Hughes A., Pierce I., Moody W., Steeds R., Puddu P., Kellman P., Savvatis K., Mohiddin S., Moon J., Barison A., Piras P., Captur G.

JACC. Cardiovascular imaging, 2025


An Automated User-friendly Software for Fast Computation of Blood Flow Velocity From Coronary Angiographic Images.

Çap M., Karaduman M., Zhou T., Erdoğan E., Tanboğa İ., Tufaro V., He X., Bajaj R., Yap N., Khan A., Koo B., Rakhit R., Karamasis G., Abdulelah Z., Hughes A., Serruys P., Mathur A., Baumbach A., Torii R., Aben J., Bourantas C.

Angiology, 2025


Sex differences between mid-life glycaemic traits and brain volume at age 70: a population-based study.

Fatih N., Hughes A., Sudre C., Chaturvedi N., Garfield V., Silverwood R., Ploubidis G., Parker T., Lu K., Cash D., Malone I., Wong A., Barnes J., Richards M., Fox N., Schott J., James S.

European journal of endocrinology, 2025


Genetic and Lifestyle Risks for Coronary Artery Disease and Long-Term Risk of Incident Dementia Subtypes.

Sittichokkananon A., Garfield V., Chiesa S.

Circulation, 2025


Associations of life-course cardiovascular risk factors with late-life cerebral hemodynamics.

Dijsselhof M., Holtrop J., James S., Sudre C., Lu K., Lorenzini L., Collij L., Scott C., Manning E., Thomas D., Richards M., Hughes A., Cash D., Barkhof F., Schott J., Petr J., Mutsaerts H.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2025


Demographic-Based Personalized Left Ventricular Hypertrophy Thresholds for Hypertrophic Cardiomyopathy Diagnosis.

Shiwani H., Davies R., Topriceanu C., Ditaranto R., Owens A., Raman B., Augusto J., Hughes R., Torlasco C., Dowsing B., Artico J., Joy G., Miranda I., Witschey W., Rodriguez-Palomares J., Badia-Molins C., Crotti L., Cortina-Borja M., Chuang M., Kwong R., Kramer C., Manning W., Ho C., Kellman P., Hughes A., Biagini E., Mohiddin S., Lopes L., Litt H., Ferrari V., Captur G., Moon J.

Journal of the American College of Cardiology, 2025


Life course trajectories of maternal cardiovascular disease risk factors by obstetric history: a UK cohort study using electronic health records.

Birnie K., Howe L., Jones T., Madley-Dowd P., Martin F., Forbes H., Redaniel M., Cornish R., Magnus M., Davies N., Tilling K., Hughes A., Lawlor D., Fraser A.

BMC medicine, 2025


Higher Aircraft Noise Exposure Is Linked to Worse Heart Structure and Function by Cardiovascular MRI.

Topriceanu C., Gong X., Shah M., Shiwani H., Eminson K., Atilola G., Jephcote C., Adams K., Blangiardo M., Moon J., Hughes A., Gulliver J., Rowlands A., Chaturvedi N., O'Regan D., Hansell A., Captur G.

Journal of the American College of Cardiology, 2025


Tissue Doppler echocardiography predicts long-term cardiovascular mortality: the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) legacy 20-year follow-up study.

Ratneswaren A., Wu T., Kaura A., Wasan D., Rostamian S., Sharp A., Poulter N., Sever P., Stanton A., Thom S., Francis D., Hughes A., Shah A., Mayet J.

Open heart, 2025


Positive association of oscillometrically estimated baseline arterial stiffness with incident diabetes and prediabetes: A large population-based cohort study.

Beros A., Sluyter J., Hughes A., Hametner B., Wassertheurer S., Scragg R.

Primary care diabetes, 2025


Device-Measured 24-Hour Movement Behaviors and Blood Pressure: A 6-Part Compositional Individual Participant Data Analysis in the ProPASS Consortium.

Blodgett J., Ahmadi M., Atkin A., Pulsford R., Rangul V., Chastin S., Chan H., Suorsa K., Bakker E., Gupta N., Hettiarachchi P., Johansson P., Sherar L., Del Pozo Cruz B., Koemel N., Mishra G., Eijsvogels T., Stenholm S., Hughes A., Teixeira-Pinto A., Ekelund U., Lee I., Holtermann A., Koster A., Stamatakis E., Hamer M.

Circulation, 2025


Childhood adiposity underlies numerous adult brain traits commonly attributed to midlife obesity.

Chiesa S., Rader L., Garfield V., Foote I., Suri S., Davey Smith G., Hughes A., Richardson T.

Brain : a journal of neurology, 2025


A machine learning algorithm for creating isotropic 3D aortic segmentations from routine cardiac MR localizers.

Jiang Y., Punjabi K., Pierce I., Knight D., Yao T., Steeden J., Hughes A., Muthurangu V., Davies R.

Magnetic resonance imaging, 2025


A guide to consumer-grade wearables in cardiovascular clinical care and population health for non-experts.

Jamieson A., Chico T., Jones S., Chaturvedi N., Hughes A., Orini M.

NPJ cardiovascular health, 2025


Multi-cohort, multi-sequence harmonisation for cerebrovascular brain age.

Dijsselhof M., Moore C., Amiri S., Tee M., Hilal S., Chen C., van den Born B., Nordhøy W., Andreassen O., Westlye L., Chaturvedi N., Hughes A., Cash D., Schott J., Sudre C., Barkhof F., Kuijer J., Biondo F., Cole J., Mutsaerts H., Petr J.

Imaging neuroscience (Cambridge, Mass.), 2025


2024


Association of early life cardiovascular risk factors with grey matter structure in young adults in the United Kingdom: the ALSPAC study.

Haines H., Suri S., Patel R., Chiesa S.

EBioMedicine, 2024


Aortic reservoir-excess pressure parameters are associated with worse cognitive function in people with untreated stage II/III hypertension.

Aizawa K., Jordan A., Gooding K., Llewellyn D., Mawson D., Casanova F., Gates P., Adingupu D., Elyas S., Hope S., Gilchrist M., Strain W., Clark C., Bellenger N., Sharp A., Parker K., Hughes A., Shore A.

Journal of hypertension, 2024


Next generation brain health: transforming global research and public health to promote prevention of dementia and reduce its risk in young adult populations.

Farina F., Bridgeman K., Gregory S., Crivelli L., Foote I., Jutila O., Kucikova L., Mariano L., Nguyen K., Thayanandan T., Akindejoye F., Butler J., Calandri I., Čepukaitytė G., Chiesa S., Dawson W., Deckers K., Cruz-Góngora V., Dounavi M., Govia I., Guzmán-Vélez E., Heikal S., Hill-Jarrett T., Ibáñez A., James B., McGlinchey E., Mullin D., Muniz-Terrera G., Pintado Caipa M., Qansuwa E., Robinson L., Santuccione Chadha A., Shannon O., Su L., Weidner W., Booi L.

The lancet. Healthy longevity, 2024


High-Resolution MRA Cerebrovascular Findings in a Tri-Ethnic Population.

Rehwald R., Sudre C., Smith L., Sokolska M., Tillin T., Atkinson D., Chaturvedi N., Hughes A., Jäger H.

AJNR. American journal of neuroradiology, 2024


Advancing the access to cardiovascular diagnosis and treatment among women with cardiovascular disease: a joint British Cardiovascular Societies' consensus document.

Tayal U., Pompei G., Wilkinson I., Adamson D., Sinha A., Hildick-Smith D., Cubbon R., Garbi M., Ingram T., Colebourn C., Camm C., Guzik T., Anderson L., Page S., Wicks E., Jenkins P., Rosen S., Eftychiou S., Roberts E., Eftekhari H., Probert H., Cowie A., Thakkar R., Moore J., Berry C., Captur G., Deshpande A., Brown S., Malkin R., Harrison M., Lawson C., Ng G., Kunadian V.

Heart (British Cardiac Society), 2024


Accuracy of smartwatches for the remote assessment of exercise capacity.

Jamieson A., Jones S., Chaturvedi N., Hughes A., Orini M.

Scientific reports, 2024


Reservoir-excess pressure parameters are independently associated with NT-proBNP in older adults.

Aizawa K., Hughes A., Casanova F., Gooding K., Gates P., Mawson D., Williams J., Goncalves I., Nilsson J., Khan F., Colhoun H., Palombo C., Parker K., Shore A.

ESC heart failure, 2024


Arterial Stiffness and Incident Glaucoma: A Large Population-Based Cohort Study.

Beros A., Sluyter J., Hughes A., Hametner B., Wassertheurer S., Scragg R.

American journal of ophthalmology, 2024


Adulthood adiposity affects cardiac structure and function in later life.

Al Saikhan L., Chaturvedi N., Ghosh A., Hardy R., Hughes A.

European heart journal, 2024


Thomas (Tom) B. Bolton - a major force in smooth muscle research.

Zholos A., Greenwood I., Lang R., Benham C., Aaronson P., Garland C., Weston A., Prestwich S., Gordienko D., Povstyan O., Zhang H., Clapp L., Pucovsky V., Tare M., Fenech C., Unno T., Muraki K., Shi J., Hughes A., Halstead T., Beech D.

The Journal of physiology, 2024


Reply to 'Differences between brachial and aortic blood pressure in obesity adolescents?'.

Hughes A., Chaturvedi N.

Journal of hypertension, 2024


Differences between brachial and aortic blood pressure in adolescence and their implications for diagnosis of hypertension.

Hughes A., Davey Smith G., Howe L., Lawlor D., Jones S., Park C., Chaturvedi N.

Journal of hypertension, 2024


Lung function trajectories from school age to adulthood and their relationship with markers of cardiovascular disease risk.

Granell R., Haider S., Deliu M., Ullah A., Mahmoud O., Fontanella S., Lowe L., Simpson A., Dodd J., Arshad S., Murray C., Roberts G., Hughes A., Park C., Holloway J., Custovic A.

Thorax, 2024


Long COVID and financial outcomes: evidence from four longitudinal population surveys.

Rhead R., Wels J., Moltrecht B., Shaw R., Silverwood R., Zhu J., Hughes A., Chaturvedi N., Demou E., Katikireddi S., Ploubidis G.

Journal of epidemiology and community health, 2024


Relationship of device measured physical activity type and posture with cardiometabolic health markers: pooled dose-response associations from the Prospective Physical Activity, Sitting and Sleep Consortium.

Ahmadi M., Blodgett J., Atkin A., Chan H., Del Pozo Cruz B., Suorsa K., Bakker E., Pulsford R., Mielke G., Johansson P., Hettiarachchi P., Thijssen D., Stenholm S., Mishra G., Teixeira-Pinot A., Rangul V., Sherar L., Ekelund U., Hughes A., Lee I., Holtermann A., Koster A., Hamer M., Stamatakis E.

Diabetologia, 2024


Arterial stiffness and incident chronic kidney disease: a large population-based cohort study.

Beros A., Sluyter J., Hughes A., Hametner B., Wassertheurer S., Scragg R.

Journal of nephrology, 2024


Long COVID and cardiovascular disease: a prospective cohort study.

Lawson C., Moss A., Arnold J., Bagot C., Banerjee A., Berry C., Greenwood J., Hughes A., Khunti K., Mills N., Neubauer S., Raman B., Sattar N., Leavy O., Richardson M., Elneima O., McAuley H., Shikotra A., Singapuri A., Sereno M., Saunders R., Harris V., Houchen-Wolloff L., Greening N., Harrison E., Docherty A., Lone N., Quint J., Chalmers J., Ho L., Horsley A., Marks M., Poinasamy K., Evans R., Wain L., Brightling C., McCann G.

Open heart, 2024


Socioeconomic inequalities in cardiovascular disease: a causal perspective.

Bann D., Wright L., Hughes A., Chaturvedi N.

Nature reviews. Cardiology, 2024


APOE ε4 carriage associates with improved myocardial performance from adolescence to older age.

Topriceanu C., Shah M., Webber M., Chan F., Shiwani H., Richards M., Schott J., Chaturvedi N., Moon J., Hughes A., Hingorani A., O'Regan D., Captur G.

BMC cardiovascular disorders, 2024


Electrophysiological Characterization of Subclinical and Overt Hypertrophic Cardiomyopathy by Magnetic Resonance Imaging-Guided Electrocardiography.

Joy G., Lopes L., Webber M., Ardissino A., Wilson J., Chan F., Pierce I., Hughes R., Moschonas K., Shiwani H., Jamieson R., Velazquez P., Vijayakumar R., Dall'Armellina E., Macfarlane P., Manisty C., Kellman P., Davies R., Tome M., Koncar V., Tao X., Guger C., Rudy Y., Hughes A., Lambiase P., Moon J., Orini M., Captur G.

Journal of the American College of Cardiology, 2024


Characterizing the Causal Pathway From Childhood Adiposity to Right Heart Physiology and Pulmonary Circulation Using Lifecourse Mendelian Randomization.

Leyden G., Urquijo H., Hughes A., Davey Smith G., Richardson T.

Journal of the American Heart Association, 2024


Associations of carotid atherosclerosis with cognitive function and brain health: Findings from a UK tri-ethnic cohort study (Southall and Brent Revisited).

Anbar R., Jones S., Chaturvedi N., Sudre C., Richards M., Sultan S., Hughes A.

Atherosclerosis plus, 2024


Examining how well economic evaluations capture the value of mental health.

Lathe J., Silverwood R., Hughes A., Patalay P.

The lancet. Psychiatry, 2024


Common infections and neuroimaging markers of dementia in three UK cohort studies.

Green R., Sudre C., Warren-Gash C., Butt J., Waterboer T., Hughes A., Schott J., Richards M., Chaturvedi N., Williams D.

Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024


Early-life cumulative exposure to excess bodyweight and midlife cognitive function: longitudinal analysis in three British birth cohorts.

Chiesa S., Norris T., Garfield V., Richards M., Hughes A.

The lancet. Healthy longevity, 2024


Device-measured physical activity and cardiometabolic health: the Prospective Physical Activity, Sitting, and Sleep (ProPASS) consortium.

Blodgett J., Ahmadi M., Atkin A., Chastin S., Chan H., Suorsa K., Bakker E., Hettiarcachchi P., Johansson P., Sherar L., Rangul V., Pulsford R., Mishra G., Eijsvogels T., Stenholm S., Hughes A., Teixeira-Pinto A., Ekelund U., Lee I., Holtermann A., Koster A., Stamatakis E., Hamer M.

European heart journal, 2024


Mechanisms underlying exercise intolerance in long COVID: An accumulation of multisystem dysfunction.

Jamieson A., Al Saikhan L., Alghamdi L., Hamill Howes L., Purcell H., Hillman T., Heightman M., Treibel T., Orini M., Bell R., Scully M., Hamer M., Chaturvedi N., Montgomery H., Hughes A., Astin R., Jones S.

Physiological reports, 2024


Updating the study protocol: Insight 46 - a longitudinal neuroscience sub-study of the MRC National Survey of Health and Development - phases 2 and 3.

Murray-Smith H., Barker S., Barkhof F., Barnes J., Brown T., Captur G., R E Cartlidge M., Cash D., Coath W., Davis D., Dickson J., Groves J., Hughes A., James S., Keshavan A., Keuss S., King-Robson J., Lu K., Malone I., Nicholas J., Rapala A., Scott C., Street R., Sudre C., Thomas D., Wong A., Wray S., Zetterberg H., Chaturvedi N., Fox N., Crutch S., Richards M., Schott J.

BMC neurology, 2024


A short review of application of near-infrared spectroscopy (NIRS) for the assessment of microvascular post-occlusive reactive hyperaemia (PORH) in skeletal muscle.

Hendrick E., Jamieson A., Chiesa S., Hughes A., Jones S.

Frontiers in physiology, 2024


Near-infrared spectroscopy (NIRS)

Tandirerung F., Jamieson A., Hendrick E., Hughes A., Jones S.

Frontiers in physiology, 2024


2024 Recommendations for Validation of Noninvasive Arterial Pulse Wave Velocity Measurement Devices.

Spronck B., Terentes-Printzios D., Avolio A., Boutouyrie P., Guala A., Jerončić A., Laurent S., Barbosa E., Baulmann J., Chen C., Chirinos J., Daskalopoulou S., Hughes A., Mahmud A., Mayer C., Park J., Pierce G., Schutte A., Urbina E., Wilkinson I., Segers P., Sharman J., Tan I., Vlachopoulos C., Weber T., Bianchini E., Bruno R.

Hypertension (Dallas, Tex. : 1979), 2024


Where is VALDO? VAscular Lesions Detection and segmentatiOn challenge at MICCAI 2021.

Sudre C., Van Wijnen K., Dubost F., Adams H., Atkinson D., Barkhof F., Birhanu M., Bron E., Camarasa R., Chaturvedi N., Chen Y., Chen Z., Chen S., Dou Q., Evans T., Ezhov I., Gao H., Girones Sanguesa M., Gispert J., Gomez Anson B., Hughes A., Ikram M., Ingala S., Jaeger H., Kofler F., Kuijf H., Kutnar D., Lee M., Li B., Lorenzini L., Menze B., Molinuevo J., Pan Y., Puybareau E., Rehwald R., Su R., Shi P., Smith L., Tillin T., Tochon G., Urien H., van der Velden B., van der Velpen I., Wiestler B., Wolters F., Yilmaz P., de Groot M., Vernooij M., de Bruijne M.

Medical image analysis, 2024


Bayesian dynamic network modelling: an application to metabolic associations in cardiovascular diseases.

Molinari M., Cremaschi A., De Iorio M., Chaturvedi N., Hughes A., Tillin T.

Journal of applied statistics, 2024


2023


Socioeconomic representativeness of Australian, Canadian and British cohorts from the paediatric diabetes AdDIT study: comparisons to regional and national data.

Mahmud F., Clarke A., Elia Y., Curtis J., Benitez-Aguirre P., Cameron F., Chiesa S., Clarson C., Couper J., Craig M., Dalton R., Daneman D., Davis E., Deanfield J., Donaghue K., Jones T., Marshall S., Neil A., Marcovecchio M.

BMC medicine, 2023


Technical development and feasibility of a reusable vest to integrate cardiovascular magnetic resonance with electrocardiographic imaging.

Webber M., Joy G., Bennett J., Chan F., Falconer D., Shiwani H., Davies R., Krausz G., Tanackovic S., Guger C., Gonzalez P., Martin E., Wong A., Rapala A., Direk K., Kellman P., Pierce I., Rudy Y., Vijayakumar R., Chaturvedi N., Hughes A., Moon J., Lambiase P., Tao X., Koncar V., Orini M., Captur G.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2023


Pulse wave velocity during re-feeding and with weight gain in underweight female adolescents with anorexia nervosa.

Hudson L., Al-Khairulla H., Maicoo M., Borja M., Rapala A., Viner R., Nicholls D., Taylor A., Muthurangu V., Hughes A.

Journal of human hypertension, 2023


Long-term association of ultra-short heart rate variability with cardiovascular events.

Orini M., van Duijvenboden S., Young W., Ramírez J., Jones A., Hughes A., Tinker A., Munroe P., Lambiase P.

Scientific reports, 2023


Accelerated DNA methylation age plays a role in the impact of cardiovascular risk factors on the human heart.

Topriceanu C., Dev E., Ahmad M., Hughes R., Shiwani H., Webber M., Direk K., Wong A., Ugander M., Moon J., Hughes A., Maddock J., Schlegel T., Captur G.

Clinical epigenetics, 2023


Cardiovascular and health cost impacts of cuff blood pressure underestimation and overestimation of invasive aortic systolic blood pressure.

Fonseca R., Palmer A., Picone D., Cox I., Schultz M., Black J., Bos W., Cheng H., Chen C., Cremer A., Dwyer N., Hughes A., Lacy P., Omboni S., Ott C., Pereira T., Pucci G., Schmieder R., Wang J., Weber T., Westerhof B., Williams B., Sharman J.

Journal of hypertension, 2023


Is Height

Taylor H., Chaturvedi N., Davey Smith G., Ferreira D., Fraser A., Howe L., Hughes A., Lawlor D., Timpson N., Park C.

Hypertension (Dallas, Tex. : 1979), 2023


Assessment of Microvascular Disease in Heart and Brain by MRI: Application in Heart Failure with Preserved Ejection Fraction and Cerebral Small Vessel Disease.

Bennett J., van Dinther M., Voorter P., Backes W., Barnes J., Barkhof F., Captur G., Hughes A., Sudre C., Treibel T.

Medicina (Kaunas, Lithuania), 2023


Conventional heart failure therapy in cardiac ATTR amyloidosis.

Ioannou A., Massa P., Patel R., Razvi Y., Porcari A., Rauf M., Jiang A., Cabras G., Filisetti S., Bolhuis R., Bandera F., Venneri L., Martinez-Naharro A., Law S., Kotecha T., Virsinskaite R., Knight D., Emdin M., Petrie A., Lachmann H., Wechelakar A., Petrie M., Hughes A., Freemantle N., Hawkins P., Whelan C., McMurray J., Gillmore J., Fontana M.

European heart journal, 2023


Arterial pulse wave modeling and analysis for vascular-age studies: a review from VascAgeNet.

Alastruey J., Charlton P., Bikia V., Paliakaite B., Hametner B., Bruno R., Mulder M., Vennin S., Piskin S., Khir A., Guala A., Mayer C., Mynard J., Hughes A., Segers P., Westerhof B.

American journal of physiology. Heart and circulatory physiology, 2023


Evaluation of a portable retinal imaging device: towards a comparative quantitative analysis for morphological measurements of retinal blood vessels.

Martinez-Perez M., Hughes A., Thom S., Parker K., Witt N.

Royal Society open science, 2023


Adverse childhood experiences and the development of multimorbidity across adulthood-a national 70-year cohort study.

Chandrasekar R., Lacey R., Chaturvedi N., Hughes A., Patalay P., Khanolkar A.

Age and ageing, 2023


Home working and social and mental wellbeing at different stages of the COVID-19 pandemic in the UK: Evidence from 7 longitudinal population surveys.

Wels J., Wielgoszewska B., Moltrecht B., Booth C., Green M., Hamilton O., Demou E., Di Gessa G., Huggins C., Zhu J., Santorelli G., Silverwood R., Kopasker D., Shaw R., Hughes A., Patalay P., Steves C., Chaturvedi N., Porteous D., Rhead R., Katikireddi S., Ploubidis G.

PLoS medicine, 2023


Developing a medical device-grade T

Topriceanu C., Fornasiero M., Seo H., Webber M., Keenan K., Stupic K., Bruehl R., Ittermann B., Price K., McGrath L., Pang W., Hughes A., Nezafat R., Kellman P., Pierce I., Moon J., Captur G.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2023


Apolipoprotein Proteomics for Residual Lipid-Related Risk in Coronary Heart Disease.

Clarke R., Von Ende A., Schmidt L., Yin X., Hill M., Hughes A., Pechlaner R., Willeit J., Kiechl S., Watkins H., Theofilatos K., Hopewell J., Mayr M.

Circulation research, 2023


Sex Differences in Blood Pressure and Potential Implications for Cardiovascular Risk Management.

Picone D., Stoneman E., Cremer A., Schultz M., Otahal P., Hughes A., Black J., Bos W., Chen C., Cheng H., Dwyer N., Lacy P., Laugesen E., Liang F., Kim H., Ohte N., Okada S., Omboni S., Ott C., Pereira T., Pucci G., Rajani R., Schmieder R., Sinha M., Stewart R., Stouffer G., Takazawa K., Wang J., Weber T., Westerhof B., Williams B., Yamada H., Sharman J.

Hypertension (Dallas, Tex. : 1979), 2023


Ethnic differences in hypertension management, medication use and blood pressure control in UK primary care, 2006-2019: a retrospective cohort study.

Eastwood S., Hughes A., Tomlinson L., Mathur R., Smeeth L., Bhaskaran K., Chaturvedi N.

The Lancet regional health. Europe, 2023


Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes.

Schmidt A., Joshi R., Gordillo-Marañón M., Drenos F., Charoen P., Giambartolomei C., Bis J., Gaunt T., Hughes A., Lawlor D., Wong A., Price J., Chaturvedi N., Wannamethee G., Franceschini N., Kivimaki M., Hingorani A., Finan C.

Communications medicine, 2023


The atrial and ventricular myocardial proteome of end-stage lamin heart disease.

Topriceanu C., Alfarih M., Hughes A., Shiwani H., Chan F., Mohiddin S., Moody W., Steeds R., O'Brien B., Vowinckel J., Syrris P., Coats C., Pettit S., Arbustini E., Moon J., Captur G.

Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology, 2023


Evaluation of Microvascular Rarefaction in Vascular Cognitive Impairment and Heart Failure (CRUCIAL): Study Protocol for an Observational Study.

van Dinther M., Bennett J., Thornton G., Voorter P., Ezponda Casajús A., Hughes A., Captur G., Holtackers R., Staals J., Backes W., Bastarika G., Jones E., González A., van Oostenbrugge R., Treibel T.

Cerebrovascular diseases extra, 2023


Sex-differences in associations of LV structure and function measured by echocardiography with long-term risk of mortality and cardiovascular morbidity.

Al Saikhan L., Park C., Tillin T., Jones S., Francis D., Mayet J., Chaturvedi N., Hughes A.

Frontiers in cardiovascular medicine, 2023


Cardiometabolic risk factors, peripheral arterial tonometry and metformin in adults with type 1 diabetes participating in the REducing with MetfOrmin Vascular Adverse Lesions trial.

Chen D., Jenkins A., Greenlaw N., Dudman K., Fernandes T., Carty D., Hughes A., Januszewski A., Stehouwer C., Petrie J.

Diabetes & vascular disease research, 2023


Does 3D-speckle tracking echocardiography improve prediction of major cardiovascular events in a multi-ethnic general population? A Southall and Brent Revisited (SABRE) cohort study.

Al Saikhan L., Park C., Tillin T., Jones S., Mayet J., Chaturvedi N., Hughes A.

PloS one, 2023


2022


Functional proteomic profiling links deficient DNA clearance with increased mortality in individuals with severe COVID-19 pneumonia.

Aramburu I., Hoving D., Vernardis S., Tin M., Ioannou M., Temkin M., De Vasconcelos N., Demichev V., Helbig E., Lippert L., Stahl K., White M., Radbruch H., Ihlow J., Horst D., Chiesa S., Deanfield J., David S., Bode C., Kurth F., Ralser M., Papayannopoulos V.

Immunity, 2022


Cerebral perfusion in untreated, controlled, and uncontrolled hypertension.

Christie I., Windsor R., Mutsaerts H., Tillin T., Sudre C., Hughes A., Golay X., Gourine A., Hosford P.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2022


Juvenile idiopathic arthritis polygenic risk scores are associated with cardiovascular phenotypes in early adulthood: a phenome-wide association study.

Clarke S., Jones H., Sharp G., Easey K., Hughes A., Ramanan A., Relton C.

Pediatric rheumatology online journal, 2022


Metabolomic profiles predict individual multidisease outcomes.

Buergel T., Steinfeldt J., Ruyoga G., Pietzner M., Bizzarri D., Vojinovic D., Upmeier Zu Belzen J., Loock L., Kittner P., Christmann L., Hollmann N., Strangalies H., Braunger J., Wild B., Chiesa S., Spranger J., Klostermann F., van den Akker E., Trompet S., Mooijaart S., Sattar N., Jukema J., Lavrijssen B., Kavousi M., Ghanbari M., Ikram M., Slagboom E., Kivimaki M., Langenberg C., Deanfield J., Eils R., Landmesser U.

Nature medicine, 2022


Characterisation of ethnic differences in DNA methylation between UK-resident South Asians and Europeans.

Elliott H., Burrows K., Min J., Tillin T., Mason D., Wright J., Santorelli G., Davey Smith G., Lawlor D., Hughes A., Chaturvedi N., Relton C.

Clinical epigenetics, 2022


Comparison between cuff-based and invasive systolic blood pressure amplification.

Bui T., Picone D., Schultz M., Armstrong M., Peng X., Black J., Dwyer N., Roberts-Thomson P., Adams H., Hughes A., Sharman J.

Journal of hypertension, 2022


Reservoir Pressure Integral Is Independently Associated With the Reduction in Renal Function in Older Adults.

Aizawa K., Hughes A., Casanova F., Gates P., Mawson D., Gooding K., Gilchrist M., Goncalves I., Nilsson J., Khan F., Colhoun H., Palombo C., Parker K., Shore A.

Hypertension (Dallas, Tex. : 1979), 2022


The UK Coronavirus Job Retention Scheme and smoking, alcohol consumption and vaping during the COVID-19 pandemic: evidence from eight longitudinal population surveys.

Green M., Maddock J., Di Gessa G., Wielgoszewska B., Parsons S., Griffith G., Croft J., Stevenson A., Huggins C., Booth C., Wels J., Silverwood R., Patalay P., Hughes A., Chaturvedi N., Howe L., Fitzsimons E., Katikireddi S., Ploubidis G.

BMC medicine, 2022


Mental and social wellbeing and the UK coronavirus job retention scheme: Evidence from nine longitudinal studies.

Jacques Wels, Booth C., Wielgoszewska B., Green M., Di Gessa G., Huggins C., Griffith G., Kwong A., Bowyer R., Maddock J., Patalay P., Silverwood R., Fitzsimons E., Shaw R., Thompson E., Steptoe A., Hughes A., Chaturvedi N., Steves C., Katikireddi S., Ploubidis G.

Social science & medicine (1982), 2022


Antihypertensive treatment effect on exercise blood pressure and exercise capacity in older adults.

Jones S., Schultz M., Park C., Tillin T., Chaturvedi N., Hughes A.

Journal of hypertension, 2022


Association between carotid atherosclerosis and brain activation patterns during the Stroop task in older adults: An fNIRS investigation.

Mason S., Al Saikhan L., Jones S., James S., Murray-Smith H., Rapala A., Williams S., Sudre C., Wong B., Richards M., Fox N., Hardy R., Schott J., Chaturvedi N., Hughes A.

NeuroImage, 2022


Correction: The UK Coronavirus Job Retention Scheme and diet, physical activity, and sleep during the COVID-19 pandemic: evidence from eight longitudinal population surveys.

Wielgoszewska B., Maddock J., Green M., Di Gessa G., Parsons S., Griffith G., Croft J., Stevenson A., Booth C., Silverwood R., Bann D., Patalay P., Hughes A., Chaturvedi N., Howe L., Fitzsimons E., Katikireddi S., Ploubidis G.

BMC medicine, 2022


Saturation-pulse prepared heart-rate independent inversion-recovery (SAPPHIRE) biventricular T1 mapping: inter-field strength, head-to-head comparison of diastolic, systolic and dark-blood measurements.

Alfarih M., Augusto J., Knott K., Fatih N., Kumar M., Boubertakh R., Hughes A., Moon J., Weingärtner S., Captur G.

BMC medical imaging, 2022


The effect of perinatal HIV and antiretroviral therapy on vascular structure and function in young people: A systematic review and meta-analysis.

Majonga E., Ferrand R., Deanfield J., Chiesa S.

Atherosclerosis, 2022


A lifecourse mendelian randomization study highlights the long-term influence of childhood body size on later life heart structure.

O'Nunain K., Park C., Urquijo H., Leyden G., Hughes A., Davey Smith G., Richardson T.

PLoS biology, 2022


Relationship Between Image Quality and Bias in 3D Echocardiographic Measures: Data From the SABRE (Southall and Brent Revisited) Study.

Al Saikhan L., Park C., Tillin T., Lloyd G., Mayet J., Chaturvedi N., Hughes A.

Journal of the American Heart Association, 2022


Urinary albumin/creatinine ratio tertiles predict risk of diabetic retinopathy progression: a natural history study from the Adolescent Cardio-Renal Intervention Trial (AdDIT) observational cohort.

Benitez-Aguirre P., Marcovecchio M., Chiesa S., Craig M., Wong T., Davis E., Cotterill A., Couper J., Cameron F., Mahmud F., Neil H., Jones T., Hodgson L., Dalton R., Marshall S., Deanfield J., Dunger D., Donaghue K.

Diabetologia, 2022


Is carotid artery atherosclerosis associated with poor cognitive function assessed using the Mini-Mental State Examination? A systematic review and meta-analysis.

Anbar R., Sultan S., Al Saikhan L., Alkharaiji M., Chaturvedi N., Hardy R., Richards M., Hughes A.

BMJ open, 2022


The UK Coronavirus Job Retention Scheme and diet, physical activity, and sleep during the COVID-19 pandemic: evidence from eight longitudinal population surveys.

Wielgoszewska B., Maddock J., Green M., Di Gessa G., Parsons S., Griffith G., Croft J., Stevenson A., Booth C., Silverwood R., Bann D., Patalay P., Hughes A., Chaturvedi N., Howe L., Fitzsimons E., Katikireddi S., Ploubidis G.

BMC medicine, 2022


Study protocol: MyoFit46-the cardiac sub-study of the MRC National Survey of Health and Development.

Webber M., Falconer D., AlFarih M., Joy G., Chan F., Davie C., Hamill Howes L., Wong A., Rapala A., Bhuva A., Davies R., Morton C., Aguado-Sierra J., Vazquez M., Tao X., Krausz G., Tanackovic S., Guger C., Xue H., Kellman P., Pierce I., Schott J., Hardy R., Chaturvedi N., Rudy Y., Moon J., Lambiase P., Orini M., Hughes A., Captur G.

BMC cardiovascular disorders, 2022


Sex-related differences in whole brain volumes at age 70 in association with hyperglycemia during adult life.

Fatih N., Chaturvedi N., Lane C., Parker T., Lu K., Cash D., Malone I., Silverwood R., Wong A., Barnes J., Sudre C., Richards M., Fox N., Schott J., Hughes A., James S.

Neurobiology of aging, 2022


Glycoprotein Acetyls: A Novel Inflammatory Biomarker of Early Cardiovascular Risk in the Young.

Chiesa S., Charakida M., Georgiopoulos G., Roberts J., Stafford S., Park C., Mykkänen J., Kähönen M., Lehtimäki T., Ala-Korpela M., Raitakari O., Pietiäinen M., Pussinen P., Muthurangu V., Hughes A., Sattar N., Timpson N., Deanfield J.

Journal of the American Heart Association, 2022


Physical activity and cardiovascular risk: No such thing as 'Too little, too late'.

Chiesa S., Charakida M.

European journal of preventive cardiology, 2022


The Roles of Neutrophils Linking Periodontitis and Atherosclerotic Cardiovascular Diseases.

Irwandi R., Chiesa S., Hajishengallis G., Papayannopoulos V., Deanfield J., D'Aiuto F.

Frontiers in immunology, 2022


Skeletal Muscle Tissue Saturation Changes Measured Using Near Infrared Spectroscopy During Exercise Are Associated With Post-Occlusive Reactive Hyperaemia.

Jones S., Tillin T., Williams S., Rapala A., Chaturvedi N., Hughes A.

Frontiers in physiology, 2022


Declining Levels and Bioavailability of IGF-I in Cardiovascular Aging Associate With QT Prolongation-Results From the 1946 British Birth Cohort.

Charalambous C., Moon J., Holly J., Chaturvedi N., Hughes A., Captur G.

Frontiers in cardiovascular medicine, 2022


Accelerated vascular aging: Ethnic differences in basilar artery length and diameter, and its association with cardiovascular risk factors and cerebral small vessel disease.

Sudre C., Moriconi S., Rehwald R., Smith L., Tillin T., Barnes J., Atkinson D., Ourselin S., Chaturvedi N., Hughes A., Jäger H., Cardoso M.

Frontiers in cardiovascular medicine, 2022


Type 2 diabetes risks and determinants in second-generation migrants and mixed ethnicity people of South Asian and African Caribbean descent in the UK.

Farmaki A., Garfield V., Eastwood S., Farmer R., Mathur R., Giannakopoulou O., Patalay P., Kuchenbaecker K., Sattar N., Hughes A., Bhaskaran K., Smeeth L., Chaturvedi N.

Diabetologia, 2022


Multiphysics Modelling and Simulation of Thrombolysis via Activated Platelet-Targeted Nanomedicine.

Gu B., Huang Y., Manchester E., Hughes A., Thom S., Chen R., Xu X.

Pharmaceutical research, 2022


Carotid atherosclerosis in people of European, South Asian and African Caribbean ethnicity in the Southall and Brent revisited study (SABRE).

Anbar R., Chaturvedi N., Eastwood S., Tillin T., Hughes A.

Frontiers in cardiovascular medicine, 2022


2021


Changes in the behavioural determinants of health during the COVID-19 pandemic: gender, socioeconomic and ethnic inequalities in five British cohort studies.

Bann D., Villadsen A., Maddock J., Hughes A., Ploubidis G., Silverwood R., Patalay P.

Journal of epidemiology and community health, 2021


Passive leg movement: A novel method to assess vascular function during passive leg heating?

Koch Esteves N., Chiesa S.

Experimental physiology, 2021


Prognostic Value of Pulmonary Transit Time and Pulmonary Blood Volume Estimation Using Myocardial Perfusion CMR.

Seraphim A., Knott K., Menacho K., Augusto J., Davies R., Pierce I., Joy G., Bhuva A., Xue H., Treibel T., Cooper J., Petersen S., Fontana M., Hughes A., Moon J., Manisty C., Kellman P.

JACC. Cardiovascular imaging, 2021


Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics.

Gordillo-Marañón M., Zwierzyna M., Charoen P., Drenos F., Chopade S., Shah T., Engmann J., Chaturvedi N., Papacosta O., Wannamethee G., Wong A., Sofat R., Kivimaki M., Price J., Hughes A., Gaunt T., Lawlor D., Gaulton A., Hingorani A., Schmidt A., Finan C.

Nature communications, 2021


Childhood Bradycardia Associates With Atrioventricular Conduction Defects in Older Age: A Longitudinal Birth Cohort Study.

Topriceanu C., Moon J., Hardy R., Hughes A., Captur G.

Journal of the American Heart Association, 2021


Impact of lockdown on key workers: findings from the COVID-19 survey in four UK national longitudinal studies.

Topriceanu C., Wong A., Moon J., Hughes A., Chaturvedi N., Conti G., Bann D., Patalay P., Captur G.

Journal of epidemiology and community health, 2021


Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.

Schmidt A., Hunt N., Gordillo-Marañón M., Charoen P., Drenos F., Kivimaki M., Lawlor D., Giambartolomei C., Papacosta O., Chaturvedi N., Bis J., O'Donnell C., Wannamethee G., Wong A., Price J., Hughes A., Gaunt T., Franceschini N., Mook-Kanamori D., Zwierzyna M., Sofat R., Hingorani A., Finan C.

Nature communications, 2021


Effect of a Multicomponent Intervention on Antihypertensive Medication Intensification in Rural South Asia: Post Hoc Analysis of a Cluster RCT.

Feng L., Jehan I., de Silva H., Naheed A., Khan A., Kasturiratne A., Clemens J., Lim C., Hughes A., Chaturvedi N., Jafar T.

American journal of hypertension, 2021


Childhood vascular phenotypes have differing associations with prenatal and postnatal growth.

Sletner L., Crozier S., Inskip H., Godfrey K., Mahon P., Chiesa S., Charakida M., Cooper C., Hanson M.

Journal of hypertension, 2021


Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.

Min J., Hemani G., Hannon E., Dekkers K., Castillo-Fernandez J., Luijk R., Carnero-Montoro E., Lawson D., Burrows K., Suderman M., Bretherick A., Richardson T., Klughammer J., Iotchkova V., Sharp G., Al Khleifat A., Shatunov A., Iacoangeli A., McArdle W., Ho K., Kumar A., Söderhäll C., Soriano-Tárraga C., Giralt-Steinhauer E., Kazmi N., Mason D., McRae A., Corcoran D., Sugden K., Kasela S., Cardona A., Day F., Cugliari G., Viberti C., Guarrera S., Lerro M., Gupta R., Bollepalli S., Mandaviya P., Zeng Y., Clarke T., Walker R., Schmoll V., Czamara D., Ruiz-Arenas C., Rezwan F., Marioni R., Lin T., Awaloff Y., Germain M., Aïssi D., Zwamborn R., van Eijk K., Dekker A., van Dongen J., Hottenga J., Willemsen G., Xu C., Barturen G., Català-Moll F., Kerick M., Wang C., Melton P., Elliott H., Shin J., Bernard M., Yet I., Smart M., Gorrie-Stone T., Shaw C., Al Chalabi A., Ring S., Pershagen G., Melén E., Jiménez-Conde J., Roquer J., Lawlor D., Wright J., Martin N., Montgomery G., Moffitt T., Poulton R., Esko T., Milani L., Metspalu A., Perry J., Ong K., Wareham N., Matullo G., Sacerdote C., Panico S., Caspi A., Arseneault L., Gagnon F., Ollikainen M., Kaprio J., Felix J., Rivadeneira F., Tiemeier H., van IJzendoorn M., Uitterlinden A., Jaddoe V., Haley C., McIntosh A., Evans K., Murray A., Räikkönen K., Lahti J., Nohr E., Sørensen T., Hansen T., Morgen C., Binder E., Lucae S., Gonzalez J., Bustamante M., Sunyer J., Holloway J., Karmaus W., Zhang H., Deary I., Wray N., Starr J., Beekman M., van Heemst D., Slagboom P., Morange P., Trégouët D., Veldink J., Davies G., de Geus E., Boomsma D., Vonk J., Brunekreef B., Koppelman G., Alarcón-Riquelme M., Huang R., Pennell C., van Meurs J., Ikram M., Hughes A., Tillin T., Chaturvedi N., Pausova Z., Paus T., Spector T., Kumari M., Schalkwyk L., Visscher P., Davey Smith G., Bock C., Gaunt T., Bell J., Heijmans B., Mill J., Relton C.

Nature genetics, 2021


Socioeconomic inequalities in prevalence and development of multimorbidity across adulthood: A longitudinal analysis of the MRC 1946 National Survey of Health and Development in the UK.

Khanolkar A., Chaturvedi N., Kuan V., Davis D., Hughes A., Richards M., Bann D., Patalay P.

PLoS medicine, 2021


Limited value of pulse wave analysis in assessing arterial wave reflection and stiffness in the pulmonary artery.

Su J., Simonsen U., Mellemkjaer S., Howard L., Manisty C., Hughes A.

Physiological reports, 2021


Physiological and clinical insights from reservoir-excess pressure analysis.

Armstrong M., Schultz M., Hughes A., Picone D., Sharman J.

Journal of human hypertension, 2021


Cardiorespiratory fitness, fatness, and the acute blood pressure response to exercise in adolescence.

Huang Z., Park C., Chaturvedi N., Howe L., Sharman J., Hughes A., Schultz M.

Scandinavian journal of medicine & science in sports, 2021


Remote Ischemic Preconditioning Protects Against Endothelial Dysfunction in a Human Model of Systemic Inflammation: A Randomized Clinical Trial.

Orlandi M., Masi S., Bhowruth D., Leira Y., Georgiopoulos G., Yellon D., Hingorani A., Chiesa S., Hausenloy D., Deanfield J., D'Aiuto F.

Arteriosclerosis, thrombosis, and vascular biology, 2021


Age matters: differences in exercise-induced cardiovascular remodelling in young and middle aged healthy sedentary individuals.

Torlasco C., D'Silva A., Bhuva A., Faini A., Augusto J., Knott K., Benedetti G., Jones S., Zalen J., Scully P., Lobascio I., Parati G., Lloyd G., Hughes A., Manisty C., Sharma S., Moon J.

European journal of preventive cardiology, 2021


Metabolic profiles of socio-economic position: a multi-cohort analysis.

Robinson O., Carter A., Ala-Korpela M., Casas J., Chaturvedi N., Engmann J., Howe L., Hughes A., Järvelin M., Kähönen M., Karhunen V., Kuh D., Shah T., Ben-Shlomo Y., Sofat R., Lau C., Lehtimäki T., Menon U., Raitakari O., Ryan A., Providencia R., Smith S., Taylor J., Tillin T., Viikari J., Wong A., Hingorani A., Kivimäki M., Vineis P.

International journal of epidemiology, 2021


Reservoir-Excess Pressure Parameters Independently Predict Cardiovascular Events in Individuals With Type 2 Diabetes.

Aizawa K., Casanova F., Gates P., Mawson D., Gooding K., Strain W., Östling G., Nilsson J., Khan F., Colhoun H., Palombo C., Parker K., Shore A., Hughes A.

Hypertension (Dallas, Tex. : 1979), 2021


Metformin and carotid intima-media thickness in never-smokers with type 1 diabetes: The REMOVAL trial.

Timmons J., Greenlaw N., Boyle J., Chaturvedi N., Ford I., Brouwers M., Tillin T., Hramiak I., Hughes A., Jenkins A., Klein B., Klein R., Ooi T., Rossing P., Stehouwer C., Sattar N., Colhoun H., Petrie J.

Diabetes, obesity & metabolism, 2021


Patients with aortic stenosis exhibit early improved endothelial function following transcatheter aortic valve replacement: The eFAST study.

Comella A., Michail M., Chan J., Cameron J., Gooley R., Mathur A., Hughes A., Brown A.

International journal of cardiology, 2021


Fibrinogen-mimicking, multiarm nanovesicles for human thrombus-specific delivery of tissue plasminogen activator and targeted thrombolytic therapy.

Huang Y., Gu B., Salles-Crawley I., Taylor K., Yu L., Ren J., Liu X., Emerson M., Longstaff C., Hughes A., Thom S., Xu X., Chen R.

Science advances, 2021


Cardiovascular disease recurrence and long-term mortality in a tri-ethnic British cohort.

Vyas M., Chaturvedi N., Hughes A., Marmot M., Tillin T.

Heart (British Cardiac Society), 2021


Distinct Body Mass Index Trajectories to Young-Adulthood Obesity and Their Different Cardiometabolic Consequences.

Norris T., Mansukoski L., Gilthorpe M., Hamer M., Hardy R., Howe L., Hughes A., Li L., O'Donnell E., Ong K., Ploubidis G., Silverwood R., Viner R., Johnson W.

Arteriosclerosis, thrombosis, and vascular biology, 2021


Puberty timing and markers of cardiovascular structure and function at 25 years: a prospective cohort study.

Maher G., Ryan L., McCarthy F., Hughes A., Park C., Fraser A., Howe L., Kearney P., O'Keeffe L.

BMC medicine, 2021


Evaluating access to health and care services during lockdown by the COVID-19 survey in five UK national longitudinal studies.

Topriceanu C., Wong A., Moon J., Hughes A., Bann D., Chaturvedi N., Patalay P., Conti G., Captur G.

BMJ open, 2021


Longitudinal birth cohort study finds that life-course frailty associates with later-life heart size and function.

Topriceanu C., Moon J., Hardy R., Chaturvedi N., Hughes A., Captur G.

Scientific reports, 2021


Excess pressure as an analogue of blood flow velocity.

Armstrong M., Schultz M., Hughes A., Picone D., Black J., Dwyer N., Roberts-Thomson P., Sharman J.

Journal of hypertension, 2021


Corrigendum to "Estimation of maximal oxygen consumption and heart rate recovery using the Tecumseh sub-maximal step test and their relationship to cardiovascular risk factors" [Artery Research 18 (June 2017) 29-35].

Hughes A., Chaturvedi N.

Artery research, 2021


Sex differences in the contribution of different physiological systems to physical function in older adults.

Jones S., Schultz M., Tillin T., Park C., Williams S., Chaturvedi N., Hughes A.

GeroScience, 2021


Identifying Isolated Systolic Hypertension From Upper-Arm Cuff Blood Pressure Compared With Invasive Measurements.

Picone D., Schultz M., Armstrong M., Black J., Bos W., Chen C., Cheng H., Cremer A., Dwyer N., Hughes A., Kim H., Lacy P., Laugesen E., Liang F., Ohte N., Okada S., Omboni S., Ott C., Pereira T., Pucci G., Schmieder R., Sinha M., Stouffer G., Takazawa K., Roberts-Thomson P., Wang J., Weber T., Westerhof B., Williams B., Sharman J.

Hypertension (Dallas, Tex. : 1979), 2021


Determinants of Intima-Media Thickness in the Young: The ALSPAC Study.

Chiesa S., Charakida M., Georgiopoulos G., Dangardt F., Wade K., Rapala A., Bhowruth D., Nguyen H., Muthurangu V., Shroff R., Davey Smith G., Lawlor D., Sattar N., Timpson N., Hughes A., Deanfield J.

JACC. Cardiovascular imaging, 2021


Preventing Cardiovascular Complications in Type 1 Diabetes: The Need for a Lifetime Approach.

Chiesa S., Marcovecchio M.

Frontiers in pediatrics, 2021


Study Protocol: The Heart and Brain Study.

Suri S., Bulte D., Chiesa S., Ebmeier K., Jezzard P., Rieger S., Pitt J., Griffanti L., Okell T., Craig M., Chappell M., Blockley N., Kivimäki M., Singh-Manoux A., Khir A., Hughes A., Deanfield J., Jensen D., Green S., Sigutova V., Jansen M., Zsoldos E., Mackay C.

Frontiers in physiology, 2021


Feasibility and Validity of Computed Tomography-Derived Fractional Flow Reserve in Patients With Severe Aortic Stenosis: The CAST-FFR Study.

Michail M., Ihdayhid A., Comella A., Thakur U., Cameron J., McCormick L., Gooley R., Nicholls S., Mathur A., Hughes A., Ko B., Brown A.

Circulation. Cardiovascular interventions, 2021


Antihypertensive Medication Use and Its Effects on Blood Pressure and Haemodynamics in a Tri-ethnic Population Cohort: Southall and Brent Revisited (SABRE).

Hughes A., Eastwood S., Tillin T., Chaturvedi N.

Frontiers in cardiovascular medicine, 2021


Blood pressure variability and night-time dipping assessed by 24-hour ambulatory monitoring: Cross-sectional association with cardiac structure in adolescents.

Goudswaard L., Harrison S., Van De Klee D., Chaturvedi N., Lawlor D., Davey Smith G., Hughes A., Howe L.

PloS one, 2021


Corrigendum: Imaging Protocol, Feasibility, and Reproducibility of Cardiovascular Phenotyping in a Large Tri-Ethnic Population-Based Study of Older People: The Southall and Brent Revisited (SABRE) Study.

Al Saikhan L., Alobaida M., Bhuva A., Chaturvedi N., Heasman J., Hughes A., Jones S., Eastwood S., Manisty C., March K., Ghosh A., Mayet J., Oguntade A., Tillin T., Williams S., Wright A., Park C.

Frontiers in cardiovascular medicine, 2021


Establishing reference intervals for triglyceride-containing lipoprotein subfraction metabolites measured using nuclear magnetic resonance spectroscopy in a UK population.

Joshi R., Wannamethee G., Engmann J., Gaunt T., Lawlor D., Price J., Papacosta O., Shah T., Tillin T., Whincup P., Chaturvedi N., Kivimaki M., Kuh D., Kumari M., Hughes A., Casas J., Humphries S., Hingorani A., Schmidt A.

Annals of clinical biochemistry, 2021


2020


Associations between arterial stiffening and brain structure, perfusion, and cognition in the Whitehall II Imaging Sub-study: A retrospective cohort study.

Suri S., Chiesa S., Zsoldos E., Mackay C., Filippini N., Griffanti L., Mahmood A., Singh-Manoux A., Shipley M., Brunner E., Kivimäki M., Deanfield J., Ebmeier K.

PLoS medicine, 2020


Vascular Effects of ACE (Angiotensin-Converting Enzyme) Inhibitors and Statins in Adolescents With Type 1 Diabetes.

Chiesa S., Marcovecchio M., Benitez-Aguirre P., Cameron F., Craig M., Couper J., Davis E., Dalton R., Daneman D., Donaghue K., Jones T., Mahmud F., Marshall S., Neil H., Dunger D., Deanfield J.

Hypertension (Dallas, Tex. : 1979), 2020


Angiographic Functional Scoring of Coronary Artery Disease Predicts Mortality in Patients With Severe Aortic Stenosis Undergoing TAVR.

Michail M., Thakur U., Comella A., Lim R., Gupta V., Tan S., Rashid H., Cameron J., Nicholls S., McCormick L., Gooley R., Mathur A., Hughes A., Brown A.

Cardiovascular revascularization medicine : including molecular interventions, 2020


The modified arterial reservoir: An update with consideration of asymptotic pressure (

Hughes A., Parker K.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 2020


Subclinical macro and microvascular disease is differently associated with depressive symptoms in men and women: Findings from the SABRE population-based study.

Wang J., Tillin T., Hughes A., Richards M., Sattar N., Park C., Chaturvedi N.

Atherosclerosis, 2020


Biomarkers associated with early stages of kidney disease in adolescents with type 1 diabetes.

Marcovecchio M., Colombo M., Dalton R., McKeigue P., Benitez-Aguirre P., Cameron F., Chiesa S., Couper J., Craig M., Daneman D., Davis E., Deanfield J., Donaghue K., Jones T., Mahmud F., Marshall S., Neil A., Colhoun H., Dunger D.

Pediatric diabetes, 2020


Role of the Metabolic Profile in Mediating the Relationship Between Body Mass Index and Left Ventricular Mass in Adolescents: Analysis of a Prospective Cohort Study.

Carter A., Santos Ferreira D., Taylor A., Lawlor D., Davey Smith G., Sattar N., Chaturvedi N., Hughes A., Howe L.

Journal of the American Heart Association, 2020


Cohort Profile Update: Southall and Brent Revisited (SABRE) study: a UK population-based comparison of cardiovascular disease and diabetes in people of European, South Asian and African Caribbean heritage.

Jones S., Tillin T., Park C., Williams S., Rapala A., Al Saikhan L., Eastwood S., Richards M., Hughes A., Chaturvedi N.

International journal of epidemiology, 2020


Triglyceride-containing lipoprotein sub-fractions and risk of coronary heart disease and stroke: A prospective analysis in 11,560 adults.

Joshi R., Wannamethee S., Engmann J., Gaunt T., Lawlor D., Price J., Papacosta O., Shah T., Tillin T., Chaturvedi N., Kivimaki M., Kuh D., Kumari M., Hughes A., Casas J., Humphries S., Hingorani A., Schmidt A.

European journal of preventive cardiology, 2020


Weight Loss After Bariatric Surgery Significantly Improves Carotid and Cardiac Function in Apparently Healthy People with Morbid Obesity.

Giudici A., Palombo C., Kozakova M., Morizzo C., Losso L., Nannipieri M., Berta R., Hughes A., Cruickshank J., Khir A.

Obesity surgery, 2020


Cuff Under Pressure for Greater Accuracy.

Picone D., Schultz M., Hughes A., Sharman J.

Current hypertension reports, 2020


Recreational marathon running does not cause exercise-induced left ventricular hypertrabeculation.

D'Silva A., Captur G., Bhuva A., Jones S., Bastiaenen R., Abdel-Gadir A., Gati S., van Zalen J., Willis J., Malhotra A., Ster I., Manisty C., Hughes A., Lloyd G., Sharma R., Moon J., Sharma S.

International journal of cardiology, 2020


Genetic aetiology of blood pressure relates to aortic stiffness with bi-directional causality: evidence from heritability, blood pressure polymorphisms, and Mendelian randomization.

Cecelja M., Keehn L., Ye L., Spector T., Hughes A., Chowienczyk P.

European heart journal, 2020


Study Protocol - Insight 46 Cardiovascular: A Sub-study of the MRC National Survey of Health and Development.

Mason S., Al Saikhan L., Jones S., Bale G., James S., Murray-Smith H., Rapala A., Williams S., Wong B., Richards M., Fox N., Hardy R., Schott J., Chaturvedi N., Hughes A.

Artery research, 2020


Modelling ethnic differences in the distribution of insulin resistance via Bayesian nonparametric processes: an application to the SABRE cohort study.

Molinari M., de Iorio M., Chaturvedi N., Hughes A., Tillin T.

The international journal of biostatistics, 2020


Non-invasive assessment of ventriculo-arterial coupling using aortic wave intensity analysis combining central blood pressure and phase-contrast cardiovascular magnetic resonance.

Bhuva A., D'Silva A., Torlasco C., Nadarajan N., Jones S., Boubertakh R., Van Zalen J., Scully P., Knott K., Benedetti G., Augusto J., Bastiaenen R., Lloyd G., Sharma S., Moon J., Parker K., Manisty C., Hughes A.

European heart journal. Cardiovascular Imaging, 2020


Inline perfusion mapping provides insights into the disease mechanism in hypertrophic cardiomyopathy.

Camaioni C., Knott K., Augusto J., Seraphim A., Rosmini S., Ricci F., Boubertakh R., Xue H., Hughes R., Captur G., Lopes L., Brown L., Manisty C., Petersen S., Plein S., Kellman P., Mohiddin S., Moon J.

Heart (British Cardiac Society), 2020


Acute Effects of Transcatheter Aortic Valve Replacement on Central Aortic Hemodynamics in Patients With Severe Aortic Stenosis.

Michail M., Hughes A., Comella A., Cameron J., Gooley R., McCormick L., Mathur A., Parker K., Brown A., Cameron J.

Hypertension (Dallas, Tex. : 1979), 2020


The influence of fitness on exercise blood pressure and its association with cardiac structure in adolescence.

Huang Z., Fonseca R., Sharman J., Park C., Chaturvedi N., Howe L., Hughes A., Schultz M.

Scandinavian journal of medicine & science in sports, 2020


Effect of adiposity on differences in carotid plaque burden in studies conducted in Norway and Russia: a cross-sectional analysis of two populations at very different risk of cardiovascular mortality.

Imahori Y., Frost C., Mathiesen E., Ryabikov A., Kudryavtsev A., Malyutina S., Kornev M., Hughes A., Hopstock L., Leon D.

BMJ open, 2020


Medication Adherence During Adjunct Therapy With Statins and ACE Inhibitors in Adolescents With Type 1 Diabetes.

Niechciał E., Acerini C., Chiesa S., Stevens T., Dalton R., Daneman D., Deanfield J., Jones T., Mahmud F., Marshall S., Neil H., Dunger D., Marcovecchio M.

Diabetes care, 2020


Adolescent health and future cardiovascular disability: it's never too early to think about prevention.

Chiesa S., Charakida M., Deanfield J.

European heart journal, 2020


Yoga-Based Cardiac Rehabilitation After Acute Myocardial Infarction: A Randomized Trial.

Prabhakaran D., Chandrasekaran A., Singh K., Mohan B., Chattopadhyay K., Chadha D., Negi P., Bhat P., Sadananda K., Ajay V., Singh K., Praveen P., Devarajan R., Kondal D., Soni D., Mallinson P., Manchanda S., Madan K., Hughes A., Chathurvedi N., Roberts I., Ebrahim S., Reddy K., Tandon N., Pocock S., Roy A., Kinra S.

Journal of the American College of Cardiology, 2020


Carotid intima media thickness in older children and adolescents with HIV taking antiretroviral therapy.

Majonga E., Chiesa S., McHugh G., Mujuru H., Nathoo K., Odland J., Kaski J., Ferrand R.

Medicine, 2020


The association between anthropometric measures of adiposity and the progression of carotid atherosclerosis.

Imahori Y., Mathiesen E., Morgan K., Frost C., Hughes A., Hopstock L., Johnsen S., Emaus N., Leon D.

BMC cardiovascular disorders, 2020


Influence of Renal Transplantation and Living Kidney Donation on Large Artery Stiffness and Peripheral Vascular Resistance.

Buus N., Carlsen R., Hughes A., Skov K.

American journal of hypertension, 2020


Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta-Analysis in Up to 16 126 Participants.

Borges M., Schmidt A., Jefferis B., Wannamethee S., Lawlor D., Kivimaki M., Kumari M., Gaunt T., Ben-Shlomo Y., Tillin T., Menon U., Providencia R., Dale C., Gentry-Maharaj A., Hughes A., Chaturvedi N., Casas J., Hingorani A.

Journal of the American Heart Association, 2020


Influence of Age on Upper Arm Cuff Blood Pressure Measurement.

Picone D., Schultz M., Otahal P., Black J., Bos W., Chen C., Cheng H., Cremer A., Dwyer N., Fonseca R., Hughes A., Kim H., Lacy P., Laugesen E., Ohte N., Omboni S., Ott C., Pereira T., Pucci G., Roberts-Thomson P., Rossen N., Schmieder R., Sueta D., Takazawa K., Wang J., Weber T., Westerhof B., Williams B., Yamada H., Yamamoto E., Sharman J.

Hypertension (Dallas, Tex. : 1979), 2020


Correction: Age-specific reference values for carotid arterial stiffness estimated by ultrasonic wall tracking.

Uejima T., Dunstan F., Arbustini E., Łoboz-Grudzień K., Hughes A., Carerj S., Favalli V., Antonini-Canterin F., Vriz O., Vinereanu D., Zamorano J., Popescu B., Evangelista A., Lancellotti P., Lefthériotis G., Kozakova M., Palombo C., Fraser A.

Journal of human hypertension, 2020


Type 2 diabetes does not account for ethnic differences in exercise capacity or skeletal muscle function in older adults.

Jones S., Tillin T., Williams S., Eastwood S., Hughes A., Chaturvedi N.

Diabetologia, 2020


Age-specific reference values for carotid arterial stiffness estimated by ultrasonic wall tracking.

Uejima T., Dunstan F., Arbustini E., Łoboz-Grudzień K., Hughes A., Carerj S., Favalli V., Antonini-Canterin F., Vriz O., Vinereanu D., Zamorano J., Popescu B., Evangelista A., Lancellotti P., Lefthériotis G., Kozakova M., Palombo C., Fraser A.

Journal of human hypertension, 2020


Associations between family history and coronary artery calcium and coronary heart disease in British Europeans and South Asians.

Wang J., Tillin T., Hughes A., Chaturvedi N.

International journal of cardiology, 2020


Training for a First-Time Marathon Reverses Age-Related Aortic Stiffening.

Bhuva A., D'Silva A., Torlasco C., Jones S., Nadarajan N., Van Zalen J., Chaturvedi N., Lloyd G., Sharma S., Moon J., Hughes A., Manisty C.

Journal of the American College of Cardiology, 2020


Cardiovascular Remodeling Experienced by Real-World, Unsupervised, Young Novice Marathon Runners.

D'Silva A., Bhuva A., van Zalen J., Bastiaenen R., Abdel-Gadir A., Jones S., Nadarajan N., Menacho Medina K., Ye Y., Augusto J., Treibel T., Rosmini S., Ramlall M., Scully P., Torlasco C., Willis J., Finocchiaro G., Papatheodorou E., Dhutia H., Cole D., Chis Ster I., Hughes A., Sharma R., Manisty C., Lloyd G., Moon J., Sharma S.

Frontiers in physiology, 2020


Feasibility of Estimation of Aortic Wave Intensity Using Non-invasive Pressure Recordings in the Absence of Flow Velocity in Man.

Hughes A., Park C., Ramakrishnan A., Mayet J., Chaturvedi N., Parker K.

Frontiers in physiology, 2020


Improvements in Skeletal Muscle Can Be Detected Using Broadband NIRS in First-Time Marathon Runners.

Jones S., Kinsella M., Torlasco C., Kaynezhad P., de Roever I., Moon J., Hughes A., Bale G.

Advances in experimental medicine and biology, 2020


Associations between high blood pressure and DNA methylation.

Kazmi N., Elliott H., Burrows K., Tillin T., Hughes A., Chaturvedi N., Gaunt T., Relton C.

PloS one, 2020


Covid-19 Effects on ARTErial StIffness and Vascular AgeiNg: CARTESIAN Study Rationale and Protocol.

Bruno R., Spronck B., Hametner B., Hughes A., Lacolley P., Mayer C., Muiesan M., Rajkumar C., Terentes-Printzios D., Weber T., Hansen T., Boutouyrie P.

Artery research, 2020


Dyslipidaemias and Cardiovascular Disease: Focus on the Role of PCSK9 Inhibitors.

Panagiotopoulou O., Chiesa S., Tousoulis D., Charakida M.

Current medicinal chemistry, 2020


Mechanisms of Aortic Flow Deceleration and the Effect of Wave Reflection on Left Ventricular Function.

Park C., Hughes A., Henein M., Khir A.

Frontiers in physiology, 2020


Imaging Protocol, Feasibility, and Reproducibility of Cardiovascular Phenotyping in a Large Tri-Ethnic Population-Based Study of Older People: The Southall and Brent Revisited (SABRE) Study.

Al Saikhan L., Alobaida M., Bhuva A., Chaturvedi N., Heasman J., Hughes A., Jones S., Eastwood S., Manisty C., March K., Ghosh A., Mayet J., Oguntade A., Tillin T., Williams S., Wright A., Park C.

Frontiers in cardiovascular medicine, 2020


Correction to: Improvements in Skeletal Muscle Can Be Detected Using Broadband NIRS in First-Time Marathon Runners.

Jones S., Kinsella M., Torlasco C., Kaynezhad P., de Roever I., Moon J., Hughes A., Bale G.

Advances in experimental medicine and biology, 2020


2019


Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition.

Kettunen J., Holmes M., Allara E., Anufrieva O., Ohukainen P., Oliver-Williams C., Wang Q., Tillin T., Hughes A., Kähönen M., Lehtimäki T., Viikari J., Raitakari O., Salomaa V., Järvelin M., Perola M., Davey Smith G., Chaturvedi N., Danesh J., Di Angelantonio E., Butterworth A., Ala-Korpela M.

PLoS biology, 2019


Elevated high-density lipoprotein in adolescents with Type 1 diabetes is associated with endothelial dysfunction in the presence of systemic inflammation.

Chiesa S., Charakida M., McLoughlin E., Nguyen H., Georgiopoulos G., Motran L., Elia Y., Marcovecchio M., Dunger D., Dalton R., Daneman D., Sochett E., Mahmud F., Deanfield J.

European heart journal, 2019


Response to 'Does smoking or alcohol cause early vascular damage in teenage years?'.

Charakida M., Georgiopoulos G., Dangardt F., Chiesa S., Hughes A., Rapala A., Davey Smith G., Lawlor D., Finer N., Deanfield J.

European heart journal, 2019


Computational simulations of thrombolysis in acute stroke: Effect of clot size and location on recanalisation.

Gu B., Piebalgs A., Huang Y., Roi D., Lobotesis K., Longstaff C., Hughes A., Chen R., Thom S., Xu X.

Medical engineering & physics, 2019


Identification of Distinct Arterial Waveform Clusters and a Longitudinal Evaluation of Their Clinical Usefulness.

Sluyter J., Hughes A., Camargo C., Thom S., Parker K., Hametner B., Wassertheurer S., Scragg R.

Hypertension (Dallas, Tex. : 1979), 2019


Maternal adiposity and offspring blood pressure: a call for primordial prevention strategies.

Chiesa S., Georgiopoulos G., Charakida M.

European journal of preventive cardiology, 2019


Familial cardiomyopathy caused by a novel heterozygous mutation in the gene

Alfarih M., Syrris P., Arbustini E., Augusto J., Hughes A., Lloyd G., Lopes L., Moon J., Mohiddin S., Captur G.

Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology, 2019


The relationship between pubertal timing and markers of vascular and cardiac structure and function in men and women aged 60-64 years.

Hardy R., Maddock J., Ghosh A., Hughes A., Kuh D.

Scientific reports, 2019


Carotid artery wave intensity in mid- to late-life predicts cognitive decline: the Whitehall II study.

Chiesa S., Masi S., Shipley M., Ellins E., Fraser A., Hughes A., Patel R., Khir A., Halcox J., Singh-Manoux A., Kivimaki M., Celermajer D., Deanfield J.

European heart journal, 2019


Association between fat mass through adolescence and arterial stiffness: a population-based study from The Avon Longitudinal Study of Parents and Children.

Dangardt F., Charakida M., Georgiopoulos G., Chiesa S., Rapala A., Wade K., Hughes A., Timpson N., Pateras K., Finer N., Sattar N., Davey Smith G., Lawlor D., Deanfield J.

The Lancet. Child & adolescent health, 2019


High-Density Lipoprotein Function and Dysfunction in Health and Disease.

Chiesa S., Charakida M.

Cardiovascular drugs and therapy, 2019


Early vascular damage from smoking and alcohol in teenage years: the ALSPAC study.

Charakida M., Georgiopoulos G., Dangardt F., Chiesa S., Hughes A., Rapala A., Davey Smith G., Lawlor D., Finer N., Deanfield J.

European heart journal, 2019


Physiological and Pathophysiological Consequences of a 25-Day Ultra-Endurance Exercise Challenge.

Tiller N., Chiesa S., Roberts J., Turner L., Jones S., Romer L.

Frontiers in physiology, 2019


Prognostic implications of left ventricular strain by speckle-tracking echocardiography in the general population: a meta-analysis.

Al Saikhan L., Park C., Hardy R., Hughes A.

Vascular health and risk management, 2019


Impact of Kidney Function on Cardiovascular Risk and Mortality: A Comparison of South Asian and European Cohorts.

Eastwood S., Chaturvedi N., Sattar N., Welsh P., Hughes A., Tillin T.

American journal of nephrology, 2019


Reproducibility of Left Ventricular Dyssynchrony Indices by Three-Dimensional Speckle-Tracking Echocardiography: The Impact of Sub-optimal Image Quality.

Al Saikhan L., Park C., Hughes A.

Frontiers in cardiovascular medicine, 2019


2018


Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses.

Wade K., Chiesa S., Hughes A., Chaturvedi N., Charakida M., Rapala A., Muthurangu V., Khan T., Finer N., Sattar N., Howe L., Fraser A., Lawlor D., Davey Smith G., Deanfield J., Timpson N.

Circulation, 2018


Childhood Fat and Lean Mass: Differing Relations to Vascular Structure and Function at Age 8 to 9 Years.

Sletner L., Mahon P., Crozier S., Inskip H., Godfrey K., Chiesa S., Bhowruth D., Charakida M., Deanfield J., Cooper C., Hanson M.

Arteriosclerosis, thrombosis, and vascular biology, 2018


Intimal and medial arterial changes defined by ultra-high-frequency ultrasound: Response to changing risk factors in children with chronic kidney disease.

Dangardt F., Charakida M., Chiesa S., Bhowruth D., Rapala A., Thurn D., Schaefer F., Deanfield J., Shroff R.

PloS one, 2018


2017


Clustering of cardio-metabolic risk factors in parents of adolescents with type 1 diabetes and microalbuminuria.

Marcovecchio M., Tossavainen P., Owen K., Fullah C., Benitez-Aguirre P., Masi S., Ong K., Nguyen H., Chiesa S., Dalton R., Deanfield J., Dunger D.

Pediatric diabetes, 2017


ACE Inhibitors and Statins in Adolescents with Type 1 Diabetes.

Marcovecchio M., Chiesa S., Bond S., Daneman D., Dawson S., Donaghue K., Jones T., Mahmud F., Marshall S., Neil H., Dalton R., Deanfield J., Dunger D.

The New England journal of medicine, 2017


Statins in Peripheral Arterial Disease.

Chiesa S., Papageorgiou N., Charakida M.

Current pharmaceutical design, 2017


Short-term heat therapy: sufficient stimulus for structural vascular adaptations?

Chiesa S., Bhowruth D., Trangmar S.

The Journal of physiology, 2017


2016


Recent developments in near-infrared spectroscopy (NIRS) for the assessment of local skeletal muscle microvascular function and capacity to utilise oxygen.

Jones S., Chiesa S., Chaturvedi N., Hughes A.

Artery research, 2016


2015


Hydration and the human brain circulation and metabolism.

Trangmar S., Chiesa S., Kalsi K., Secher N., González-Alonso J.

Nutricion hospitalaria, 2015


2014


2013


2012


2011


2010